Results 211 to 220 of about 75,140 (320)

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

Neutrophil extracellular traps are increased in the airways of obese asthmatic patients. [PDF]

ERJ Open Res
Williams EJ, Wood LG, Dowling LRC, Stanton S, Baines KJ.   +4 more
europepmc   +1 more source

Reactive Oxygen Species–Induced Modifications of Fibrin Clots as a Link Between Immune Responses and Atherothrombosis in Systemic Lupus Erythematosus

Arthritis &Rheumatology, EarlyView.
Objective Cardiovascular events are major determinants of morbidity and mortality in systemic lupus erythematosus (SLE), particularly in patients with renal involvement. Although oxidative stress has been implicated in driving vascular and renal damage in SLE, the specific mechanisms remain unclear.
Matteo Becatti, Giacomo Emmi, Alessandra Bettiol, Amanda Mannucci, Flavia Rita Argento, Eleonora Fini, Serena Borghi, Francesca Nencini, Maria Nicastro, Irene Mattioli, Elena Silvestri, Augusto Vaglio, Domenico Prisco, Claudia Fiorillo   +13 more
wiley   +1 more source

Neutrophil extracellular traps associated with severity and prognosis of community-acquired pneumonia. [PDF]

Clin Exp Med
Wang Y, Xie H, Wang L, Fan J, Zhang Y, Pan S, Chen Q, Zhou W, Liu X, Wu A, Zhang H, Song L, Liu J, Wang J, Tian X.   +14 more
europepmc   +1 more source

Neutrophil Extracellular Traps in Sepsis and Sepsis-Related Organ Dysfunction. [PDF]

Immunotargets Ther
Yan W, Xu X, Li X, Ma Y, Guo L, Yang J, Jin Z, Zhang J, Li T.   +8 more
europepmc   +1 more source

A cooperative release of mitochondrial DNA from platelets and neutrophils drives an interferon signature in systemic sclerosis

Arthritis &Rheumatology, Accepted Article.
Objective Mitochondria are organelles with a hypomethylated circular genome. Mitochondrial DNA (mtDNA) in the systemic circulation has been implicated in inflammation. This study investigates the role of circulating DNA in systemic sclerosis (SSc) and the cellular mechanisms governing its release.
Stavros Giaglis, André N. Tiaden, Simone Häner‐Massimi, Diego Kyburz, Cedric André, Anton Glück, Enrico Ferrero, Stuart Hawtin, Tobias Junt, Ulrich A. Walker   +9 more
wiley   +1 more source

Dysregulation of U12‐Type Splicing in Lupus Neutrophils

Arthritis &Rheumatology, Accepted Article.
Abstract. Objective Neutrophil dysfunction is a hallmark of systemic lupus erythematosus (SLE), but its molecular basis remains unclear. This study explores transcriptional and post‐transcriptional changes in low‐density granulocytes (LDGs), a proinflammatory neutrophil subset expanded in SLE, focusing on NADPH oxidase (Nox) function and minor intron ...
Luz P. Blanco, Binod Regmi, Carmelo Carmona‐Rivera, Yudong Liu, Xiantao Wang, Philip M. Carlucci, Monica M. Jackson, Zerai Manna, Sarfaraz Hasni, Markus Hafner, Hong‐Wei Sun, Mariana J. Kaplan   +11 more
wiley   +1 more source

Emerging Topics and Trends in Neutrophil Extracellular Traps in ARDS: A Bibliometric and Visual Analysis. [PDF]

Mediators Inflamm
Wang Y, Luo Z, Fu S, Li Q, Zhang Z, Huang N, Zou K, Zou L.   +7 more
europepmc   +1 more source

Neutrophil extracellular traps: from physiology to pathology.

Cardiovascular Research, 2021
A. Hidalgo, P. Libby, O. Soehnlein, I. Aramburu, V. Papayannopoulos, C. Silvestre-Roig   +5 more
semanticscholar   +1 more source

Targeting neutrophil extracellular traps: A novel strategy for treating heterotopic ossification. [PDF]

World J Orthop
Song CY, Yu HP, Mu FY, Lu JS, Yang M, Chang MH, Wang KY.   +6 more
europepmc   +1 more source