Results 71 to 80 of about 75,140 (320)

Neutrophil extracellular traps in sheep mastitis [PDF]

Veterinary Research, 2015
Neutrophil extracellular traps (NETs) are structures composed of DNA, histones, and antimicrobial proteins that are released extracellularly by neutrophils and other immune cells as a means for trapping and killing invading pathogens. Here, we describe NET formation in milk and in mammary alveoli of mastitic sheep, and provide a dataset of proteins ...
Pisanu S., Cubeddu T., Pagnozzi D., Rocca S., Cacciotto C., Alberti A., Marogna G., Uzzau S., Addis M. F.   +8 more
openaire   +3 more sources

Netosis in the pathogenesis of antiphospholipid syndrome and systemic lupus erythematosus

Современная ревматология, 2021
Antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE) are autoimmune diseases. In recent years, APS has been considered as an autoimmune thrombo-inflammatory disease.
K. S. Nurbaeva, T. M. Reshetnyak, A. M. Lila   +2 more
doaj   +1 more source

A signature for pan-cancer prognosis based on neutrophil extracellular traps

Journal for ImmunoTherapy of Cancer, 2022
Background Neutrophil extracellular traps (NETs) were originally thought to be formed by neutrophils to trap invading microorganisms as a defense mechanism.
Yi Zhang, Li-ping Guo, Qichen Dai, Bingqing Shang, T. Xiao, Xue-bing Di, Kaitai Zhang, Lin Feng, J. Shou, Yipeng Wang   +9 more
semanticscholar   +1 more source

Nicotine induces neutrophil extracellular traps

Journal of Leukocyte Biology, 2016
Abstract NETs serve to ensnare and kill microbial pathogens. However, NETs can at the same time contribute to tissue damage and excessive inflammation. Nicotine is a major toxic agent and has been associated with exacerbated inflammatory diseases.
Hosseinzadeh, Ava, Thompson, Paul R, Segal, Brahm H., Urban, Constantin F.   +3 more
openaire   +4 more sources

Neutrophil killing of Mycobacterium abscessus by intra- and extracellular mechanisms. [PDF]

PLoS ONE, 2018
Mycobacterium abscessus, a rapidly growing nontuberculous mycobacterium, are increasingly present in soft tissue infections and chronic lung diseases, including cystic fibrosis, and infections are characterized by growth in neutrophil-rich environments ...
Kenneth C Malcolm, Silvia M Caceres, Kerstin Pohl, Katie R Poch, Audrey Bernut, Laurent Kremer, Donna L Bratton, Jean-Louis Herrmann, Jerry A Nick   +8 more
doaj   +1 more source

In vitro induction of NETosis: Comprehensive live imaging comparison and systematic review [PDF]

, 2017
__Background__ Multiple inducers of in vitro Neutrophil Extracellular Trap (NET) formation (NETosis) have been described. Since there is much variation in study design and results, our aim was to create a systematic review of NETosis inducers and perform
Abraham, T.E. (Tsion), Autar, A. (Anouchska), Beusekom, H.M.M. (Heleen) van, Cappellen, W.A. (Gert) van, Hoppenbrouwers, T. (Tamara), Houtsmuller, A.B. (Adriaan), Maat, M.P.M. (Moniek) de, Neck, J.W. (Han) van, Sultan, A.R. (Andi R.), Wamel, W.J.B. (Willem) van   +9 more
core   +1 more source

“The NET effect”: Neutrophil extracellular traps—a potential key component of the dysregulated host immune response in sepsis

Critical Care
Neutrophils release neutrophil extracellular traps (NETs) as part of a healthy host immune response. NETs physically trap and kill pathogens as well as activating and facilitating crosstalk between immune cells and complement.
Andrew Retter, M. Singer, Djillali Annane   +2 more
semanticscholar   +1 more source

Neutrophil extracellular traps and their histones promote Th17 cell differentiation directly via TLR2

Nature Communications, 2022
Neutrophils perform critical functions in the innate response to infection, including through the production of neutrophil extracellular traps (NETs) - web-like DNA structures which are extruded from neutrophils upon activation.
Alicia S. Wilson, Katrina L. Randall, J. Pettitt, J. Ellyard, A. Blumenthal, A. Enders, B. Quah, T. Bopp, C. Parish, A. Brüstle   +9 more
semanticscholar   +1 more source

Insights into pneumococcal pneumonia using lung aspirates and nasopharyngeal swabs collected from pneumonia patients in The Gambia. [PDF]

, 2020
We investigated the pathogenesis of pneumococcal pneumonia using clinical specimens collected for pneumonia surveillance in The Gambia. Lung aspirates and nasopharyngeal swabs from 31 patients were examined by culture, qPCR, whole genome sequencing ...
Dunne, EM, Hinds, J, Hossain, I, Hua, Y, Mackenzie, GA, Manna, S, Mulholland, EK, Ndiaye, M, Ortika, BD, Salaudeen, R, Satzke, C   +10 more
core   +4 more sources

Neutrophil Extracellular Traps in Host Defense [PDF]

Cold Spring Harbor Perspectives in Biology, 2019
Neutrophils are produced in the bone marrow and then patrol blood vessels from which they can be rapidly recruited to a site of infection. Neutrophils bind, engulf, and efficiently kill invading microbes via a suite of defense mechanisms. Diverse extracellular and intracellular microbes induce neutrophils to extrude neutrophil extracellular traps (NETs)
Sabrina Sofia Burgener, Kate Schroder
openaire   +3 more sources