Intersection Between Local Anesthetics and Cancer Biology: What Now? Where Are We Going?
Local anesthetics (LAs), widely used in anesthesia, may also play a role in cancer treatment by inhibiting tumor growth, reducing metastasis, and enhancing immune responses. They modulate key pathways like AKT/mTOR and RAS/ERK while affecting angiogenesis and tumor innervation and the immune response.
Eduardo Nunez‐Rodriguez+3 more
wiley +1 more source
Anti-Inflamatory Drug for Myocardial Injury in Acute Coronary Syndrome
Acute coronary syndrome (ACS) as the acute setting of coronary chronic syndrome has been widely known to have high mortality rates. ST segment elevation of myocardial infarction (STEMI) is one category of ACS which occurs when major coronary arteries are
Ryan Ranitya
doaj +2 more sources
Akute febrile neutrophile Dermatose (Sweet-Syndrom) - Eine seltene Komplikation der Colitis ulcerosa [PDF]
Antonella De Donno+1 more
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The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali+5 more
wiley +1 more source
Functional activity of blood neutrophiles in acute inflammatory diseases of the abdominal organs and abdominal tuberculosis [PDF]
В. М. Акімова+3 more
openalex +1 more source
This study introduces an extracorporeal hemoperfusion system incorporating porous microbeads embedded with autocatalytic ceria nanoparticles (CeNPs) for targeted reactive oxygen species (ROS) scavenging in septic shock. The blood‐compatible hemoperfusion cartridge demonstrated significant improvements in survival, hemodynamic stability, and organ ...
Pilseon Im+10 more
wiley +1 more source
Persistent topology for natural data analysis - A survey
Natural data offer a hard challenge to data analysis. One set of tools is being developed by several teams to face this difficult task: Persistent topology.
A Adcock+36 more
core +1 more source
Leukocyte, neutrophil, immature granulocyte counts and interleukin-6 are superior to procalcitonin, C-reactive protein and delta-He for detection of mild inflammation: data from marathon runners producing mild systemic inflammation visible immediately after the run / Leukozyten, Neutrophile, unreife Granulozyten und Interleukin-6 sind zum Nachweis geringgradiger Entzündungen Procalcitonin, C-reaktivem Protein und Delta-He überlegen: Ergebnisse aus einer Untersuchung von Marathonläufern [PDF]
Andreas Weimann+10 more
openalex +1 more source
Electric Pulse Regulated MXene Based Nanozymes for Integrative Bioelectricity Immuno‐Cancer Therapy
MXenzyme‐mediated bioelectricity cancer therapy (MXenzyme‐BECT) enhances cancer cell death through irreversible depolarization, ion channel disruption, ROS generation, and immunogenic cell death. Computational simulations reveal the electrical mechanisms by which MXenzyme acts on single cells and support to predict treatment parameters. Next‐generation
Sanghee Lee+6 more
wiley +1 more source
Background and objectives: Ankylosing spondylitis impacts the fibers and synovial tissues of the sacroiliac and spinal joint and is most noticeable commencement occurs in males.
Shahla Taha Ahmad, Shwan Kader Media
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