Granulozytäre Elastase als Marker der unspezifischen Proteolyse in der Pathogenese entzündlicher Erkrankungen [PDF]
Fritz, H.+5 more
core
[Postoperatively developing ulcerous skin lesions with associated ulcerative colitis in a patient with status after femorocrural (P3) bypass insertion for peripheral arterial occlusion disease]. [PDF]
Barth U+4 more
europepmc +1 more source
Engineered Foxp1high Exosomes Ameliorates Systemic Lupus Erythematosus
This study presents a dual‐engineering strategy combining mesenchymal stem cell aggregation and Foxp1 overexpression to generate Foxp1high aggregation exosomes with enhanced immunomodulatory properties. These engineered exosomes exhibit immune organ targeting and superior efficacy in systemic lupus erythematosus treatment by promoting Treg ...
Luhan Niu+9 more
wiley +1 more source
Clinical Manifestations and Risk Factors of Liver Injury Induced by PD-1 Inhibitors in Patients with Malignancies: A Case-Control Study. [PDF]
Zhao P, Yu L, Ma W, Zhao T.
europepmc +1 more source
This study investigates the role of group 2 innate lymphoid cells (ILC2) in the choroid plexus (ChP) following traumatic brain injury (TBI). ILC2 accumulation alleviates immune infiltration, preserves hippocampal integrity, and improves sensory‐motor and memory functions.
Shiqi Gao+10 more
wiley +1 more source
Sulfilimines: An Underexplored Bioisostere for Drug Design? [PDF]
Arvidsson PI.
europepmc +1 more source
Homeostasis of Gut Microbiota Protects against Susceptibility to Fungal Pneumonia
Fungal pneumonia induces inflammation, shown by heightened IL‐6, IL‐1β, TNF‐α levels and a growth in Staphylococcus in the alveolar flora. The gut microbiota, acting through the gut‐lung axis via blood, impacts fungal pneumonia susceptibility by altering lung metabolism and inflammatory responses.
Jian Ji+12 more
wiley +1 more source
Oberflächenrezeptoren auf Neutrophilen Granulozyten bei Patienten mit Chronischer Granulomatose [PDF]
Lehmann, Natalie
core
Felty syndrome with liver cirrhosis: A case report. [PDF]
Wan C+5 more
europepmc +1 more source
This study elucidates the critical role of Rictor in macrophage activation in acute antibody‐mediated rejection (ABMR). Rictor increases K48‐linked ubiquitination of p65 by upregulating E3 ubiquitin ligase SOCS1, inhibiting transcriptional levels of NLRP3 and inflammasome activation.
Bin Ni+12 more
wiley +1 more source