Results 51 to 60 of about 571,123 (210)

Neutrophil and neutrophil extracellular trap involvement in neutrophilic asthma: A review

Medicine
Asthma is a highly prevalent chronic inflammatory disease characterized by variable airflow obstruction and airway hyperresponsiveness. Neutrophilic asthma (NA) is classified as “type 2 low” asthma, defined as 65% or more neutrophils in the total cell count.
Yuemu Li, Tianyi Yang, Baihua Jiang
openaire   +2 more sources

Lipopolysaccharides of Fusobacterium nucleatum and Porphyromonas gingivalis increase RANKL-expressing neutrophils in air pouches of mice

Laboratory Animal Research, 2021
Increases of neutrophils and osteoclasts are pathological changes of periodontitis. RANKL is an osteoclast differentiation factor. The effect of periodontopathogen LPS on RANKL-expressing neutrophils has not been clarified yet.
Ae Ri Kim, Yun Kyong Lim, Joong-Ki Kook, Eun-Jung Bak, Yun-Jung Yoo   +4 more
doaj   +1 more source

Neutrophilic dermatoses

La Revue de Médecine Interne, 2022
Neutrophilic dermatoses (ND) are a group of inflammatory skin conditions characterized by a neutrophilic infiltrate on histopathology with no evidence of infection. ND are classified based upon the localization of neutrophils within the skin and clinical features.
Delaleu, Jeremie, Lepelletier, C., Calugareanu, A., de Masson, A., Charvet, E., Petit, A., Giurgea, Irina, Amselem, Serge, Karabina, Sonia, Jachiet, M., Mahevas, T., Ram-Wolff, C., Vignon-Pennamen, M.-D., Bagot, M., Battistella, M., Bouaziz, J.-D.   +15 more
openaire   +2 more sources

The Age-Driven Decline in Neutrophil Function Contributes to the Reduced Efficacy of the Pneumococcal Conjugate Vaccine in Old Hosts

Frontiers in Cellular and Infection Microbiology, 2022
Despite the availability of vaccines, Streptococcus pneumoniae (pneumococcus) remains a serious cause of infections in the elderly. The efficacy of anti-pneumococcal vaccines declines with age.
Shaunna R. Simmons, Essi Y. I. Tchalla, Manmeet Bhalla, Elsa N. Bou Ghanem   +3 more
doaj   +1 more source

Increased CD11b and Decreased CD62L in Blood and Airway Neutrophils from Long-Term Smokers with and without COPD

Journal of Innate Immunity, 2020
There is incomplete mechanistic understanding of the mobilization of neutrophils in the systemic and local compartment in smokers with chronic obstructive pulmonary disease (COPD).
Marit Stockfelt, Karin Christenson, Anders Andersson, Lena Björkman, Médea Padra, Bettina Brundin, Koustav Ganguly, Helga Asgeirsdottir, Sara Lindén, Ingemar Qvarfordt, Johan Bylund, Anders Lindén   +11 more
doaj   +1 more source

ATRA treatment slowed P-selectin-mediated rolling of flowing HL60 cells in a mechano-chemical-dependent manner

Frontiers in Immunology, 2023
All-trans retinoic acid (ATRA)-induced differentiation of acute promyelocytic leukemia (APL) toward granulocytes may trigger APL differentiation syndrome (DS), but there is less knowledge about the mechano-chemical regulation mechanism of APL DS under ...
Xiaoting Dong, Shiping Peng, Yingchen Ling, Bing Huang, Bing Huang, Wenjian Tu, Xiaoxi Sun, Quhuan Li, Ying Fang, Jianhua Wu   +9 more
doaj   +1 more source

EGF-induced bronchial epithelial cells drive neutrophil chemotactic and anti-apoptotic activity in asthma [PDF]

, 2013
Chronic damage and repair of the bronchial epithelium are features of asthma. We have previously reported that ex vivo stimulation of normal bronchial epithelial cells with epidermal growth factor (EGF), a key factor of epithelial repair, enhances the ...
Donna E Davies, Cornelius Victoria, Grégory Seumois, Lau, LC, Karl J Staples, Cornelius, Victoria, Dorinsky, P, Victoria Cornelius, Davies Donna E., Dinesh Bagmane (457229), Staples, Karl J., Uddin, Mohib, Ratko Djukanović, Pandurangan Vijayanand, Victoria Cornelius (457230), Lau, Laurie C., Mohib Uddin (457226), Karl J. Staples (457228), Bagmane, Dinesh, Ratko Djukanović (457232), Paul Dorinsky, Pandurangan Vijayanand (277869), Djukanović Ratko, Lau, Laurie C, Grégory Seumois (5656213), Lau Laurie C., Staples, KJ, Vijayanand, P, Vijayanand, Pandurangan, Laurie C. Lau (457227), Seumois, G, Uddin, M, Staples, Karl J, Davies, Donna E, Staples Karl J., Davies, DE, Donna E. Davies (137702), Seumois Grégory, Djukanović, R, Dinesh Bagmane, Djukanović, Ratko, Cornelius, V, Davies, Donna E., Laurie C Lau, Dorinsky Paul, Paul Dorinsky (457231), Dorinsky, Paul, Seumois, Grégory, Bagmane Dinesh, Uddin Mohib, Bagmane, D, Mohib Uddin, Vijayanand Pandurangan   +52 more
core   +2 more sources

Neutrophils isolated from systemic lupus erythematosus patients exhibit a distinct functional phenotype

Frontiers in Immunology
Neutrophil dysregulation, particularly of a low-density subset, is associated with systemic lupus erythematosus (SLE); however, the exact role of normal-density neutrophils in SLE remains unknown.
Neelakshi R. Jog, Catriona A. Wagner, Teresa Aberle, Eliza F. Chakravarty, Cristina Arriens, Joel M. Guthridge, Judith A. James, Judith A. James   +7 more
doaj   +1 more source

CD31 signaling promotes the detachment at the uropod of extravasating neutrophils allowing their migration to sites of inflammation

eLife, 2023
Effective neutrophil migration to sites of inflammation is crucial for host immunity. A coordinated cascade of steps allows intravascular leukocytes to counteract the shear stress, transmigrate through the endothelial layer, and move toward the ...
Francesco Andreata, Marc Clément, Robert A Benson, Juliette Hadchouel, Emanuele Procopio, Guillaume Even, Julie Vorbe, Samira Benadda, Véronique Ollivier, Benoit Ho-Tin-Noe, Marie Le Borgne, Pasquale Maffia, Antonino Nicoletti, Giuseppina Caligiuri   +13 more
doaj   +1 more source

Roles of mitochondria in neutrophils

Frontiers in Immunology, 2022
Neutrophils are the most abundant leukocyte in human blood. They are critical for fighting infections and are involved in inflammatory diseases. Mitochondria are indispensable for eukaryotic cells, as they control the biochemical processes of respiration
Ziming Cao, Meng Zhao, Meng Zhao, Hao Sun, Liang Hu, Yunfeng Chen, Zhichao Fan   +6 more
doaj   +1 more source