Results 81 to 90 of about 1,037,568 (240)

Network model of immune responses reveals key effectors to single and co-infection dynamics by a respiratory bacterium and a gastrointestinal helminth [PDF]

, 2012
Co-infections alter the host immune response but how the systemic and local processes at the site of infection interact is still unclear. The majority of studies on co-infections concentrate on one of the infecting species, an immune function or group of
A Graham, A Saadatpour, AJ Bancroft, AK Pathak, AK Pathak, AK Pathak, AL Graham, AP Boyd, Ashutosh K. Pathak, C Campbell, C Espinosa-Soto, C Lacroux, CA Behm, CA Blish, CA Figueiredo, CC Chen, CD Bourke, DL Abraham, DN Wolfe, EJ Pishko, ER Walsh, F Audebert, FD Finkelman, FE Cox, GB Harrison, GR Stewart, GS Kirimanjeswara, IM Cattadori, IM Cattadori, Isabella M. Cattadori, J Holmgren, J Thakar, J Thakar, J Thakar, JA Jackson, JD Turner, JE Allen, JG Fox, JS Fahel, JT Pesce, Juilee Thakar, L Glass, L Murphy, L Sanchez, Lisa Murphy, LJ Wang, M Chaves, MR Pilione, MT Brady, NG Henderson, NW Brattig, P Gueirard, P Matzinger, R Zhang, RK Grencis, RM Anthony, Rob J. De Boer, Réka Albert, S Bornholdt, S Cornell, S Li, S Mattoo, SM Assmann, SM Geiger, T Beyer, T Resende Co, TM Stock, V Haukisalmi, WI Khan, X Xu   +69 more
core   +4 more sources

Neutrophils: New insights and open questions

Science immunology, 2018
Neutrophils patrol the bloodstream and tissues to kill microbes and guide subsequent innate and adaptive immune responses. Neutrophils are the first line of defense against bacteria and fungi and help combat parasites and viruses.
K. Ley, H. Hoffman, P. Kubes, M. Cassatella, A. Zychlinsky, C. Hedrick, S. Catz   +6 more
semanticscholar   +1 more source

The proangiogenic capacity of polymorphonuclear neutrophils delineated by microarray technique and by measurement of neovascularization in wounded skin of CD18-deficient mice [PDF]

, 2006
Growing evidence supports the concept that polymorphonuclear neutrophils (PMN) are critically involved in inflammation-mediated angiogenesis which is important for wound healing and repair.
Addison CL, Armstrong DA, Baggiolini M, Barbara Walzog, Bazzoni F, Benelli R, Bernardini G, Bohnsack JF, Brandes ME, Cacalano G, Choudhuri R, Devalaraja RM, Dewald B, Dubravec DB, Gasperini S, Gaudry M, Grant DS, Grenier A, Grotendorst GR, Harada H, Heiple JM, Ikematsu S, Iruela-Arispe ML, John A, Jürgen Schymeinsky, Karin Scharffetter-Kochanek, Kreis C, Kullander K, Liu XH, Loukinova E, Matzner Y, Muramaki M, Niiro H, Oda N, Pertovaara L, Ramchandran R, Roberts AB, Ruth Schruefer, Sang QX, Sato W, Scapini P, Scharffetter-Kochanek K, Schruefer R, Sehgal I, Semenza GL, Shapiro SD, Silke Sulyok, Takada T, Takada T, Tasiemski A, Thorsten Peters, Triebel S, Walzog B, Wang SC, Willeke T, Yoshida S   +55 more
core   +1 more source

Neutrophils cultured ex vivo from CD34+ stem cells are immature and genetically tractable

Journal of Translational Medicine
Background Neutrophils are granulocytes with essential antimicrobial effector functions and short lifespans. During infection or sterile inflammation, emergency granulopoiesis leads to release of immature neutrophils from the bone marrow, serving to ...
Claire A. Naveh, Kiran Roberts, Przemysław Zakrzewski, Christopher M. Rice, Fernando M. Ponce-Garcia, Kathryn Fleming, Megan Thompson, Nawamin Panyapiean, Huan Jiang, Stephanie Diezmann, Pedro L. Moura, Ashley M. Toye, Borko Amulic   +12 more
doaj   +1 more source

Tumor-Associated Macrophages and Neutrophils in Tumor Microenvironment

Mediators of Inflammation, 2016
Distinct tumor microenvironment forms in each progression step of cancer and has diverse capacities to induce both adverse and beneficial consequences for tumorigenesis.
Jaehong Kim, J. Bae
semanticscholar   +1 more source

Shape oscillations of human neutrophil leukocytes: characterization and relationship to cell motility [PDF]

, 1996
When neutrophil leukocytes are stimulated by chemotactic factors or by substratum contact, they change their shape. Shape changes are a prerequisite for cellular migration and typically involve the extrusion of thin, veil-like lamellipods and the ...
Coates, Thomas D., Deranleau, David A., Ehrengruber, Markus U.   +2 more
core  

Neutrophil: A New Player in Metastatic Cancers

Frontiers in Immunology, 2020
The interaction between cancer cells and immune cells is important for the cancer development. However, much attention has been given to T cells and macrophages. Being the most abundant leukocytes in the blood, the functions of neutrophils in cancer have
Mengyue Wu, Mutian Ma, Zhenya Tan, Hong Zheng, Xia Liu   +4 more
doaj   +1 more source

Siglec-E promotes β2-integrin-dependent NADPH oxidase activation to suppress neutrophil recruitment to the lung [PDF]

, 2014
Siglec-E is a sialic acid-binding Ig-like lectin expressed on murine myeloid cells. It has recently been shown to function as a negative regulator of β2-integrin-dependent neutrophil recruitment to the lung following exposure to lipopolysaccharide (LPS).
Anderson, Boyle, Boyle, Chen, Chen, Doerschuk, Fisher, Franke, Gao, Grommes, Hoyal, Kielland, Kulkarni, Liu, Matthay, McMillan, Mócsai, Pollock, Segal, Segal, Segal, Zhang, Zhang, Zhang   +23 more
core   +2 more sources

Intratumoral CXCR4hi neutrophils display ferroptotic and immunosuppressive signatures in hepatoblastoma

Frontiers in Immunology
Pediatric hepatoblastoma (HB) is the most common primary liver malignancy in infants and children. With great diversity and plasticity, tumor-infiltrating neutrophils were one of the most determining factors for poor prognosis in many malignant tumors ...
Zhengjing Lu, Zhengjing Lu, Xiaolin Wang, Xiaolin Wang, Jun Feng, Wenjia Chai, Wenjia Chai, Wei Wang, Wei Wang, Qixin Wang, Qixin Wang, Shen Yang, Wei Yang, Yan Su, Wenjun Mou, Wenjun Mou, Yun Peng, Yun Peng, Huanmin Wang, Jingang Gui, Jingang Gui   +20 more
doaj   +1 more source

Neutrophils promote the development of reparative macrophages mediated by ROS to orchestrate liver repair

Nature Communications, 2019
Phagocytes, including neutrophils and macrophages, have been suggested to function in a cooperative way in the initial phase of inflammatory responses, but their interaction and integration in the resolution of inflammation and tissue repair remain ...
Wenting Yang, Yuandong Tao, Yan Wu, Xinyuan Zhao, Weijie Ye, Dianyuan Zhao, L. Fu, Caiping Tian, Jing Yang, F. He, Li Tang   +10 more
semanticscholar   +1 more source