Results 101 to 110 of about 19,421 (203)

Immunovirological treatment out- comes after 2 years of antiretroviral therapy in children living with the human immune deficiency virus in Lagos Nigeria

Nigerian Journal of Paediatrics
Background/objective: The World Health Organization (WHO) recommends routine assessment of antiretroviral treatment outcomes to detect treatment failure early and prevent the development of drug resistance. The aim of this study was to describe treatment
Nwaiwu O, Akindele AJ, Akanmu AS, Adeyemi OO   +3 more
doaj  

Measuring the overall genetic component of nevirapine pharmacokinetics and the role of selected polymorphisms [PDF]

, 2013
ObjectiveNevirapine is an important component of highly active antiretroviral therapy used in the treatment of HIV infection. There is a considerable variation in the pharmacokinetics of nevirapine and this variation can impact the efficacy and toxicity ...
Patel, Ashish, Micheli, Janine E, Shugarts, Sarah B, Martin, Jeffrey N, Bangsberg, David R, Chinn, Leslie W, Kroetz, Deanna L   +6 more
core   +1 more source

Time to undetectable viral load after highly active antiretroviral therapy initiation among HIV-infected pregnant women

, 2007
Background. There have been no clinical trials in resource-rich regions that have addressed the question of which highly active antiretroviral therapy (HAART) regimens are more effective for optimal viral response in antiretroviral-naive, human ...
Patel, D, European Collaborative Study
core  

Infant morbidity, mortality, and breast milk immunologic profiles among breast-feeding HIV-infected and HIV-uninfected women in Botswana.

, 2007
BACKGROUND: Infants of human immunodeficiency virus (HIV)-infected women have high mortality, but the immunologic integrity and protection afforded by the breast milk of HIV-infected women is unknown.
Rahkola, Jeremy T, Shapiro, Roger L, Janoff, Edward N, Stevens, Lisa, Smeaton, Laura, Wester, Carolyn, Arimi, Peter, Ndase, Patrick, Makhema, Joseph, Montano, Monty, Asmelash, Aida, Lockman, Shahin, Thior, Ibou, Kim, Soyeon, Moffat, Claire, Essex, Max   +15 more
core   +1 more source

Nevirapine-based regimens in HIV-infected antiretroviral-naive patients: systematic review and meta-analysis of randomized controlled trials.

PLoS ONE, 2013
BackgroundNevirapine belongs to the group of non-nucleoside reverse transcriptase inhibitors (NNRTIs) and is commonly administered in first-line treatment of HIV infection.ObjectiveSystematic review and meta-analysis was undertaken to compare ...
Paweł Kawalec, Joanna Kryst, Alicja Mikrut, Andrzej Pilc   +3 more
doaj   +1 more source

Do non-nucleoside reverse transcriptase inhibitors contribute to lipodystrophy?

, 2005
Lipodystrophy complications, including lipoatrophy (pathological fat loss) and metabolic complications, have emerged as important long-term toxicities associated with antiretroviral therapy in the current era. The wealth of data that has accumulated over
Nolan, D.
core  

Relationship between nevirapine trough concentration and underlying liver diseases.

, 2013
The differences for nevirapine trough concentration between lead-in and steady-state periods was observed in patients with HBV infection (A). The nevirapine trough concentration at week 4 was significantly lower than the values at week 24, 36 and 48 ...
Xiaoli Du (276582), Jing Xie (180526), Yanling Li (269030), Yang Han (269027), Taisheng Li (269024), Zhifeng Qiu (269028), Qiang Fu (129583), Min Ye (171404), Huijuan Kou (276581), Zhu Zhu (142480)   +9 more
core   +1 more source

Clinical perspectives on human genetic screening to prevent nevirapine toxicity

Nevirapine is one of the most extensively prescribed antiretroviral drugs worldwide. However, a concern is increased risk for severe toxicity when antiretroviral-naive individuals with higher CD4 T-cell counts initiate nevirapine-containing regimens ...
Mootsikapun, Piroon, Podzamczer Palter, Daniel, Ruxrungtham, Kiat, Nevirapine Toxicogenomics Study Team, Haas, David W.   +4 more
core  

Incidence and determinants of nevirapine and efavirenz-related skin rashes in West Africans: nevirapine's epitaph?

PLoS ONE, 2014
Non-nucleoside reverse transcriptase inhibitor (NNRTI) associated rash is common and frequently leads to discontinuation of NNRTIs. This study assessed the risk of developing rashes and discontinuing NNRTIs and associated factors in a large clinic in ...
Fred Stephen Sarfo, Maame Anima Sarfo, Betty Norman, Richard Phillips, David Chadwick   +4 more
doaj   +1 more source

Nevirapine plasma concentrations during follow-up 48 weeks.

, 2013
Ctrough: trough concentration of nevirapine.Cmax: peak concentration of nevirapine.Data were described as median (IQR: inter-quartile range).
Xiaoli Du (276582), Jing Xie (180526), Yanling Li (269030), Yang Han (269027), Taisheng Li (269024), Zhifeng Qiu (269028), Qiang Fu (129583), Min Ye (171404), Huijuan Kou (276581), Zhu Zhu (142480)   +9 more
core   +1 more source