Formulation, optimization, and evaluation of self-emulsifying drug delivery systems of nevirapine
Background: The aim of the present study was to formulate and optimize the self-emulsifying drug delivery systems (SEDDS) of nevirapine (NVP) by use of 22 factorial designs to enhance the oral absorption of NVP by improving its solubility, dissolution ...
Ramprasad Chintalapudi +3 more
semanticscholar +1 more source
Evaluation of a 5-year programme to prevent mother-to-child transmission of HIV infection in Northern Uganda [PDF]
Prevention of mother-to-child transmission (PMTCT) is essential in HIV/AIDS control. We analysed 2000-05 data from mother-infant pairs in our PMTCT programme in rural Uganda, examining programme utilization and outcomes, HIV transmission rates and ...
Ahoua, Laurence +9 more
core +2 more sources
Multicentric Castleman disease is a rare proliferative disease of lymphoid tissue. It has rarely been reported in Asian countries, particularly in HIV‐positive patients. Here, we report a case of Kaposi’s sarcoma herpesvirus‐associated Multicentric Castleman disease (KSHV‐MCD).
Mai-Yin Huang +6 more
wiley +1 more source
Exposure of Allium cepa root cells to zidovudine or nevirapine induces cytogenotoxic changes.
Antiretroviral drugs have proved useful in the clinical management of HIV-infected persons, though there are concerns about the effects of exposure to these DNA-reactive drugs.
Chika K Onwuamah +5 more
doaj +1 more source
BackgroundPolymorphisms in cytochrome P450 2B6 (CYP2B6) affect the steady state plasma concentration of nevirapine. CYP2B6 516G>T and 983T>C are common in African populations, but data on their influence on plasma nevirapine concentration and clinical ...
Margaret Ngwono Oluka +4 more
semanticscholar +1 more source
Pharmacokinetic Herb-Drug Interactions: Insight into Mechanisms and Consequences [PDF]
Herbal medicines are currently in high demand, and their popularity is steadily increasing. Because of their perceived effectiveness, fewer side effects and relatively low cost, they are being used for the management of numerous medical conditions ...
Horie, Toshiharu +3 more
core +1 more source
Primary HIV-1 Infection Among Infants in sub-Saharan Africa: HPTN 024. [PDF]
Our objectives were to assess clinical signs and diagnoses associated with primary HIV-1 infection among infants. We analyzed data from a clinical trial (HIV Prevention Trials Network Protocol 024) in sub-Saharan Africa.
Anthony Mwatha +26 more
core +2 more sources
SPECTROPHOTOMETRIC DETERMINATION OF NEVIRAPINE USING TETRATHIOCYANATOCOBALT(II) ION AS A REAGENT
A simple and rapid spectrophotometric method for the determination of nevirapine is described. The method is based on the reaction of nevirapine with tetrathiocyanatocobalt(II) ion in buffer of pH 4 to form the corresponding complex. Beer’s law is obeyed
T. V. Badiadka, Badiadka Narayana
doaj +1 more source
Adherence to antiretroviral therapy assessed by drug level monitoring and self-report in cameroon [PDF]
OBJECTIVES: To compare adherence to antiretroviral therapy using drug level monitoring and self-report and to explore the relation between these 2 methods and viral load measurements.
Alexandra Calmy +29 more
core +3 more sources
Second-line antiretroviral therapy in resource-limited settings: the experience of Médecins Sans Frontières [PDF]
OBJECTIVES: To describe the use of second-line protease-inhibitor regimens in Médecins Sans Frontières HIV programmes, and determine switch rates, clinical outcomes, and factors associated with survival.
Alexandra Calmy +24 more
core +2 more sources

