Results 131 to 140 of about 2,993,444 (316)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

A new combination for a Coprosma endemic to the serpentinised zone of the Surville Cliffs, North Cape, New Zealand

open access: yes, 2002
An open access copy of this article is available from the publishers website.A molecular phylogenetic analysis of New Zealand Coprosma using the internal transcribed spacer (ITS) and external transcribed spacer (ETS) regions of nrDNA discovered a ...
Wichman, S.R.   +3 more
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Topics in model averaging & toxicity models in combination therapy

open access: yes, 2015
In this dissertation we work on two problems. In the first problem we propose a general framework for frequentist model averaging and explore its applications.

core  

Exploring a new model of the cultivation of entrepreneurial talents majored in medical laboratory through combination of medicine and engineering

open access: yes, 2015
【摘要】科技和社会的发展、就业压力的加大,倒逼医学院校也探索新的教学模式解决新的压力和挑战。我们学院医工结合探索医学检验创业人才培养的新模式,我们通过:(1)改变人才培养观念、明确教育目标;(2)医工结合提供创业的条件,构建创业辅助体系,给予跨专业实践时间和资金;(3)优化考核的要求,等方法拓宽培养途径,证明医工结合培养医学检验创业人才是培养医学人才的新模式。The development of science-technology and technology and society, the ...
Su, Zhao-liang; School of Medicine, Jiangsu University, Zhenjiang, China   +1 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Patient considerations in the treatment of COPD: focus on the new combination inhaler fluticasone furoate/umeclidinium/vilanterol

open access: yes, 2018
Antonio Molino,1,* Giovanna Calabrese,1,* Mauro Maniscalco2 1Division of Pneumology, Department of Respiratory Diseases, University of Naples Federico II, AORN dei Colli-Monaldi Hospital, Naples, Italy; 2Pulmonary Rehabilitation Division, ICS Maugeri ...
Calabrese G, Molino A, Maniscalco M
core  

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

New Combinations in the Florida Flora

open access: yesNovon, 2001
New combinations are made for the following species and varieties within the flora of Florida: Agaloma oerstediana, Agaloma pubentissima, Aristida stricta var. beyrichiana, Asimina spatulata, Deeringothamnus rugelii var. pulchellus, Erianthus brevibarbis var. contortus, Ludwigia curtissii var. simpsonii, Nyssa biflora var. ursina, Pentalinon luteum var.
openaire   +2 more sources

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