Results 151 to 160 of about 8,159,296 (302)

CHAETANTHERA ACHENO-HIRSUTA (TOMBESI) ARROYO, A.M.R.DAVIES & TILL-BOTTRAUD ELEVATED TO SPECIES, NEW FOR THE FLORA OF CHILE CHAETANTHERA ACHENO-HIRSUTA (TOMBESI) ARROYO, A.M.R.DAVIES & TILL-BOTTRAUD ELEVADA A ESPECIE, NUEVA PARA LA FLORA DE CHILE

open access: yesGayana: Botanica, 2004
Chaetanthera acheno-hirsuta (Tombesi) Arroyo, A.M.R. Davies & Till-Bottraud (Asteraceae: Mutisieae), previously known from the upper limits of the vegetation (>3900m) on the eastern side of the Andes in San Juan Province, Argentina, is cited for Chile ...
Mary T.K. Arroyo   +2 more
doaj  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

New combination therapy of praziquantel and <i>Lactobacillus plantarum</i> for enhancing the treatment of clonorchiasis in mice. [PDF]

open access: yesFood Waterborne Parasitol
Ma Y   +13 more
europepmc   +1 more source

A Winning New Combination? Toward Clinical Application in Oncology. [PDF]

open access: yesCancer Control, 2023
Maqsood Q   +6 more
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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