Results 71 to 80 of about 19,296,157 (316)
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Growth and stagnation in a dual economy: The case of Brazil
PSL Quarterly Review, 2022 The aim of the present article is to further develop the line of research initiated by Oreiroet al. (2019) by expanding the database used to calculate the EQI and the EQG, but also to control the effects of variables other than the EQG, such as the ...
Carmem Feijó +2 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Howard Gardner: the myth of multiple intelligences [PDF]
, 2004 This evening I want to examine Howard Gardner’s idea that there are multiple intelligences (MI theory). MI theory identifies some eight or nine types of intelligence: not only the logico-mathematical and linguistic kinds measured by ...
White, John
core +2 more sources
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Por que novo-desenvolvimentismo? Why new-developementalism?
Brazilian Journal of Political Economy, 2007 This paper develops some general guidelines that should take part of a new view of development to Brazil, in opposition to the neoliberal project. This alternative, that is called "new developmentalism", should include sustained economic growth with ...
João Siscú +2 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
GATS and the new developmentalism: Governing transnational education [PDF]
, 2007 This article introduces a relatively recent development, the inclusion of education as a tradable service under the World Trade Organization's (WTO's) General Agreement on Trade and Services (GATS).
Sidhu, R.
core +1 more source