Results 101 to 110 of about 516,293 (285)

Strong interactions in air showers

, 2015
We study the role new gauge interactions in extensions of the standard model play in air showers initiated by ultrahigh-energy cosmic rays. Hadron-hadron events remain dominated by quantum chromodynamics, while projectiles and/or targets from beyond the ...
A. Cooper-Sarkar, D. Fargion, D.D. Dietrich, D.D. Dietrich, D.D. Dietrich, D.D. Dietrich, Dennis D. Dietrich, E. Iancu, E.A. Kuraev, E.A. Kuraev, E.A. Kuraev, E.J. Williams, G.C. Nayak, G.T. Zatsepin, HiRes collaboration, I.I. Balitsky, I.I. Balitsky, L.N. Lipatov, L.N. Lipatov, N. Arkani-Hamed, Pierre Auger collaboration, Pierre Auger collaboration, Pierre Auger collaboration, R. Bonisch, S. Yoshida, T. Hirayama, Telescope Array collaboration, V.L. Ginzburg, V.N. Gribov, V.N. Gribov, Y. Nambu, Y.L. Dokshitzer, Z. Fodor, Z. Sullivan   +33 more
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Hints of BSM physics in the SM effective potential

, 2015
Investigation of the structure of the Standard Model effective potential at very large field strengths opens a window towards new phenomena and can reveal properties of the UV completion of the SM. The map of the lifetimes of the vacua of the SM enhanced
Lalak, Zygmunt, Lewicki, Marek, Olszewski, Pawel   +2 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Prospects for discovering new gauge bosons, extra dimensions and contact interaction at the LHC

, 2008
5 pages, 4 fig, 1 tab; version 2: cosmetic changes due to ICHEP conference template ...
openaire   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Electroweak observables in neutrino-electron scattering from a muon storage ring

Journal of High Energy Physics
We investigate the sensitivity of a companion neutrino detector situated in the plane of a high-energy, high-intensity muon storage ring to elastic ν μ and ν e scattering on electrons (EνES). Assuming a muon collider with center-of-mass energies of up to
André de Gouvêa, Adrian Thompson
doaj   +1 more source

A Spin Gauge Formulation of Gravity and a New View of Gravity-Matter Interactions

, 2011
Withdrawn by author due to lack of sufficient interesting/original ...
openaire   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Exploring interference effects between two ALP effective operators at the LHC

Journal of High Energy Physics
We observe that most studies of axion-like particle (ALP) production channels at the Large Hadron Collider (LHC) focus on a single type of ALP operator for each process in the effective field theory framework.
Kingman Cheung, Chih-Ting Lu, C.J. Ouseph, Priyanka Sarmah   +3 more
doaj   +1 more source