Results 111 to 120 of about 515,250 (294)

Electroweak observables in neutrino-electron scattering from a muon storage ring

Journal of High Energy Physics
We investigate the sensitivity of a companion neutrino detector situated in the plane of a high-energy, high-intensity muon storage ring to elastic ν μ and ν e scattering on electrons (EνES). Assuming a muon collider with center-of-mass energies of up to
André de Gouvêa, Adrian Thompson
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Exploring interference effects between two ALP effective operators at the LHC

Journal of High Energy Physics
We observe that most studies of axion-like particle (ALP) production channels at the Large Hadron Collider (LHC) focus on a single type of ALP operator for each process in the effective field theory framework.
Kingman Cheung, Chih-Ting Lu, C.J. Ouseph, Priyanka Sarmah   +3 more
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Discovering quirks through timing at FASER and future forward experiments at the LHC

Journal of High Energy Physics
Quirks are generic predictions of strongly-coupled dark sectors. For weak-scale masses and a broad range of confining scales in the dark sector, quirks can be discovered only at the energy frontier, but quirk-anti-quirk pairs are produced with unusual ...
Jonathan L. Feng, Jinmian Li, Xufei Liao, Jian Ni, Junle Pei   +4 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Probing the gauge-boson couplings of axion-like particle at the LHC and high-luminosity LHC

Journal of High Energy Physics
In this work, we calculate the sensitivities on the gauge-boson couplings g aZZ , g aZγ , and g aWW of an axion-like particle (ALP) that one can achieve at the LHC with s $$ \sqrt{s} $$ = 14 TeV and integrated luminosities of 300 fb−1 (current run) and ...
Kingman Cheung, Wanyon Hsiao, C. J. Ouseph, Chen Wang   +3 more
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Improving the performance of weak supervision searches using transfer and meta-learning

Journal of High Energy Physics
Weak supervision searches have in principle the advantages of both being able to train on experimental data and being able to learn distinctive signal properties.
Hugues Beauchesne, Zong-En Chen, Cheng-Wei Chiang   +2 more
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source