Results 31 to 40 of about 20,747,688 (258)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Topics in Supersymmetry Breaking and Gauge/Gravity Dualities [PDF]

open access: yes, 2010
The thesis covers two topics in string theory and quantum field theory. First, we realize metastable vacua in various supersymmetric gauge theories. Specifically, we consider the Coulomb branch of any N = 2 supersymmetric gauge theory, and perturb it by ...
Park, Chang-Soon
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Semiclassical monopole calculations in supersymmetric gauge theories [PDF]

open access: yes, 2000
We investigate semiclassical contributions to correlation functions in N = 1 supersymmetric gauge theories. Our principal example is the gluino condensate, which signals the breaking of chiral symmetry, and should be exactly calculable, according to a ...
Davies, N.M., Davies, N Michael
core  

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Aspects of gauge/string theory duality: BMN correspondence and MHV rules [PDF]

open access: yes, 2007
One of the most striking examples of duality correspondence between gauge theories and string theories is the AdS/CFT duality. It relates the type IIB superstring theory on AdS5 x 5 5 to 4-dimensional N = 4 Yangs Mills in its superconformal phase ...
Georgiou, George
core  

Gauge Theory and Supergravity Duality in the PP-Wave Background [PDF]

open access: yes, 2005
We test the matrix theory conjecture in the pp-wave by studying two-body interactions between gravitons and membranes. We compute the one-loop effective potential of matrix theory and compare it to the light cone Lagrangian of linearized supergravity. We
Lee, Hok Kong
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Shortening the gauge argument [PDF]

open access: yes, 2012
The ``gauge argument'' is often used to `deduce' interactions from a symmetry requirement. A transition---whose justification can take some effort---from global to local transformations is typically made at the beginning of the argument.
Afriat, Alexander, Alexander Afriat
core  

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