Results 101 to 110 of about 1,362,749 (337)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Astrophysical flux of dark particles as a solution to the KM3NeT and IceCube tension over KM3-230213A

Journal of High Energy Physics
We entertain the possibility that transient astrophysical sources can produce a flux of dark particles that induce ultra-high-energy signatures at neutrino telescopes such as IceCube and KM3NeT.
Yasaman Farzan, Matheus Hostert
doaj   +1 more source

An effective up quark mass from new light particles

Physics Letters B, 1991
Abstract I consider a model where an effective current mass for the up quark is provided by the interactions of a new neutral light colored scalar and a charge 1 3 colorless fermion. The model has no strong CP problem. A new confining U (1) prevents the occurence of physical states with fractional charges.
openaire   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Searching for new light particles at the international linear collider main beam dump [PDF]

, 2021
Yasuhito Sakaki, Daiki Ueda
openalex   +1 more source

Light millicharged particles and large scale cosmic magnetic fields

, 2014
After a brief review of different types of scenarios suggested for the solution of the problem of galactic and intergalactic magnetic field generation, the mechanism based on the electric current induction by hypothetical millicharged particles ...
Dolgov, A. D.
core   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

On the Semi-classical Approach to the Physical Axiomatic of Quantum Mechanics and the New Wave-Particle Interpretation of Light [PDF]

, 2020
Andrei Nechayev
openalex   +1 more source

Search for a new heavy scalar particle decaying into a Higgs boson and a new scalar singlet in final states with one or two light leptons and a pair of $\tau$-leptons with the ATLAS detector [PDF]

, 2023
G. Aad
openalex   +1 more source

Anomaly induced effects in a magnetic field

, 2007
We consider a modification of electrodynamics by an additional light massive vector field, interacting with the photon via Chern-Simons-like coupling.
Afanasev, Ahlers, Alexey Boyarsky, Anastasopoulos, Andriamonje, Antoniadis, Antoniadis, Antoniadis, Appelquist, Arkani-Hamed, Badertscher, Bahcall, Boyarsky, Boyarsky, Cameron, Chen, Cornwall, Davidson, Davidson, Ehret, Eleftheriadis, Gies, Grinenko, Heisenberg, Ignatios Antoniadis, Maiani, Masso, Melchiorri, Mitsui, Oleg Ruchayskiy, Peccei, Peccei, Raffelt, Raffelt, Raffelt, Raffelt, Ringwald, Rizzo, Robilliard, Roncadelli, Ruoso, Schlattl, Smailagic, Van Bibber, Weinberg, Wilczek, Zavattini, Zavattini, Zavattini   +48 more
core   +1 more source