Results 41 to 50 of about 356,517 (268)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Quantum anomaly detection for collider physics

open access: yesJournal of High Energy Physics, 2023
We explore the use of Quantum Machine Learning (QML) for anomaly detection at the Large Hadron Collider (LHC). In particular, we explore a semi-supervised approach in the four-lepton final state where simulations are reliable enough for a direct ...
Sulaiman Alvi   +2 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

New light weakly-coupled particle searches in a neutrino detector

open access: yesJournal of Physics: Conference Series, 2014
Neutrino detectors at the accelerator machines of the Intensity Frontier in particle physics are becoming commonplace. As their capabilities are being understood, they seem to have the potential for studies beyond the neutrino oscillations measurements.
A Hatzikoutelis   +3 more
openaire   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Probing light neutralinos from pair-produced sleptons with displaced vertices at the high-luminosity LHC

open access: yesJournal of High Energy Physics
We study light neutralinos χ ~ 1 0 $$ \left({\overset{\sim }{\chi}}_1^0\right) $$ with masses ranging from 10 GeV to several hundred GeV within the framework of R-parity-violating (RPV) supersymmetry.
Giovanna Cottin   +4 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Searching for string bosenovas with gravitational wave detectors

open access: yesJournal of High Energy Physics
We study the phenomenology of a string bosenova explosion in vector superradiance clouds around spinning black holes, focusing on the observable consequences in gravitational wave detectors and accelerometers.
Dawid Brzeminski   +3 more
doaj   +1 more source

Search for new light particles at ILC main beam dump

open access: yes, 2020
7 pages, 5 figures.
Sakaki, Yasuhito, Ueda, Daiki
openaire   +2 more sources

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