Results 41 to 50 of about 1,332,482 (305)
FEBS Letters, EarlyView.Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer +10 more
wiley +1 more source
Novel Supersymmetric SO(10) Seesaw Mechanism [PDF]
, 2005 We propose a new seesaw mechanism for neutrino masses within a class of supersymmetric SO(10) models with broken D-parity. It is shown that in such scenarios the B-L scale can be as low as TeV without generating inconsistencies with gauge coupling ...
J. C. Romão +3 more
core +2 more sources
FEBS Letters, EarlyView.Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican +7 more
wiley +1 more source
Journal of High Energy PhysicsWe study light neutralinos χ ~ 1 0 $$ \left({\overset{\sim }{\chi}}_1^0\right) $$ with masses ranging from 10 GeV to several hundred GeV within the framework of R-parity-violating (RPV) supersymmetry.
Giovanna Cottin +4 more
doaj +1 more source
A Study of Dark Matter and QCD-Charged Mediators in the Quasi-Degenerate Regime
, 2017 We study a scenario in which the only light new particles are a Majorana fermion dark matter candidate and one or more QCD-charged scalars, which couple to light quarks. This scenario has several interesting phenomenological features if the new particles
Davidson, Andrew +4 more
core +1 more source
A New Kinematical Derivation of the Lorentz Transformation and the Particle Description of Light [PDF]
, 2022 J. H. Field
openalex +1 more source
Novel and unscrutinized immune entities of the zebrafish gut
FEBS Letters, EarlyView.Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil +5 more
wiley +1 more source
White dwarfs constraints on dark sector models with light particles
, 2013 The white dwarf luminosity function is well understood in terms of standard model physics and leaves little room for exotic cooling mechanisms related to the possible existence of new weakly interacting light particles.
Ubaldi, Lorenzo
core +1 more source
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
ALPINIST: Axion-Like Particles In Numerous Interactions Simulated and Tabulated
Journal of High Energy Physics, 2022 Proton beam dump experiments are among the most promising strategies to search for light and feebly interacting states such as axion-like particles (ALPs). The interpretation of these experiments is however complicated by the wide range of ALP models and
Jan Jerhot +4 more
doaj +1 more source