Results 51 to 60 of about 349,351 (306)
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
We study light neutralinos χ ~ 1 0 $$ \left({\overset{\sim }{\chi}}_1^0\right) $$ with masses ranging from 10 GeV to several hundred GeV within the framework of R-parity-violating (RPV) supersymmetry.
Giovanna Cottin +4 more
doaj +1 more source
LEX-EFT: the Light Exotics Effective Field Theory
We propose the creation of a Light Exotics Effective Field Theory (LEX-EFT) catalog. LEX-EFT is a generic framework to capture all interactions between the Standard Model (SM) and all (or at least a large class of) theoretically allowed exotic states ...
Linda M. Carpenter +2 more
doaj +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Searching for string bosenovas with gravitational wave detectors
We study the phenomenology of a string bosenova explosion in vector superradiance clouds around spinning black holes, focusing on the observable consequences in gravitational wave detectors and accelerometers.
Dawid Brzeminski +3 more
doaj +1 more source
Dielectric particle-based strategy to design a new self-bending subwavelength structured light beams [PDF]
Igor V. Minin, Oleg V. Minin
openalex +1 more source
Search for new light particles at ILC main beam dump
7 pages, 5 figures.
Sakaki, Yasuhito, Ueda, Daiki
openaire +2 more sources
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Baryonic dark forces in electron-beam fixed-target experiments
New GeV-scale dark forces coupling predominantly to quarks offer novel signatures that can be produced directly and searched for at high-luminosity colliders. We compute the photon-proton and electron-proton cross sections for producing a GeV-scale gauge
Safa Ben Othman +2 more
doaj +1 more source

