Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Research on the influence of new media on ideological and political education in colleges [PDF]
, 2023 E. Liu, Lanwei Zhao
openalex +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Scientific ReportsBased on deep mediatization theory and artificial intelligence (AI) technology, this study explores the effective improvement of museums’ social media communication by applying Convolutional Neural Network (CNN) technology.
Hongkai Wang, Chao Song, Hongming Li
doaj +1 more source
DUNHUANG MOGAO CAVES IMPACT ON ADOLESCENT CULTURAL HERITAGE EDUCATION WITH NEW MEDIA – A CASE STUDY ON THE DEER AND THE SNITCH [PDF]
, 2023 Jie Du, Wei-Qiang ZHANG
openalex +1 more source
High-end fashion manufacturing in the UK - product, process and vision. Recommendations for education, training and accreditation [PDF]
, 2009 The Centre for Fashion Enterprise (CFE) was commissioned by the Department of Culture, Media and Sport (DCMS) to undertake a feasibility study to explore fully the market need for a new high-end production hub.
König, Anna, Malem, Wendy, Miller, Jan
core
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Editorial: BILETA special issue: Technology and Legal Education [PDF]
, 2014 Fragmentation and convergence are two discoursal lenses that have been used to view changes that have taken place in the domains of legal services,the legal profession, regulation and legal education. While they may appear orthogon al, the relationships
Maharg, P
core +3 more sources
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source