Results 51 to 60 of about 6,474 (210)

Interactions of Cathinone NPS with Human Transporters and Receptors in Transfected Cells [PDF]

, 2017
Pharmacological assays carried out in transfected cells have been very useful for describing the mechanism of action of cathinone new psychoactive substances (NPS).
A Chamba, A Derungs, A Rickli, A Rickli, A Rickli, AJ Eshleman, AJ Eshleman, AJ Eshleman, AV Kalueff, B Bang-Andersen, B Cara Di, B Hilber, B O’Neill, BG Wilhelm, BJ Thompson, BL Murray, BT Burlingham, C Achat-Mendes, C Hysek, C Pifl, CD Verrico, CG Tate, CM Hysek, CM Hysek, CM Hysek, CM Hysek, CM Hysek, CT Bauer, D Groskreutz, D Marazziti, D Sulzer, D Viggiano, DE Nichols, DM Mueller, EA Ross, EL Barker, F Xu, FA Ran, FG Revel, G Rudnick, H Khoshbouei, HA Borek, HC Prasad, I Sora, J Talvenheimo, JJ Maguire, JO Marcusson, L Iversen, L Jing, L Simmler, LD Simmler, LD Simmler, LD Simmler, LK Henry, LL Howell, LR Watterson, LR Watterson, M Liechti, M Raiteri, M Tatsumi, M Torok, MA Mergy, ME Liechti, MH Baumann, MH Baumann, MS Mazei-Robison, MT Brown, OT Ukairo, P Scholze, PJ Nelson, R Rosenauer, R Torre de la, R Zhang, RA Johnson, RA Prosser, RB Rothman, RB Rothman, RB Rothman, RB Rothman, S Chaudhary, S Ramamoorthy, S Wee, SB Caine, SL Hill, T Steinkellner, Y Cheng, Y Schmid, Y Schmid   +87 more
core   +1 more source

Metabolic fate of drugs of abuse and new psychoactive substances: A pilot study on a novel workflow using a zebrafish embryo model combined with human microdosing

British Journal of Clinical Pharmacology, EarlyView.
Aim The aim of this study was to develop a novel workflow to identify human urine biomarkers for drugs of abuse and new psychoactive substances. Metabolites of amphetamine, cocaine, LSD, MDMA, methamphetamine, THC, MDMB‐CHMICA, and MDPPP were first identified in a zebrafish embryo (ZE) metabolism study followed by comparison to most abundant human ...
Simon K. Wellenberg, Tanja M. Gampfer, Lea Wagmann, Philip Schippers, Jennifer Herrmann, Rolf Müller, Folker Westphal, Markus R. Meyer   +7 more
wiley   +1 more source

Pattern of novel psychoactive substance use among patients presented to the poison control centre of Ain Shams University Hospitals, Egypt: A cross-sectional study

Heliyon, 2022
Background: Novel psychoactive substances (NPSs) are relatively new substances in the illicit drug market, not previously listed in the United Nations Office on Drugs and Crime (UNDOC).
Ahmed Hashim, Nouran A. Mohammed, AlFadl Othman, Mohab A.K. Gab-Allah, Ahmed H.M. Al-Kahodary, Eslam R. Gaber, Ahmed M. Hassan, Mahmoud Aranda, Rania Hussien, Amany Mokhtar, Md. Saiful Islam, Ka Yiu Lee, Muhammad Sohaib Asghar, Muhammad Junaid Tahir, Zohaib Yousaf   +14 more
doaj   +1 more source

Safety concerns reported by coroners following fentanyl patch fatalities in England, Wales and Northern Ireland between 1997 and 2024

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim To identify safety concerns reported by coroners following fentanyl patch‐related deaths in England, Wales and Northern Ireland, and determine differences in coronial reporting. Methods A systematic case series linking the National Programme on Substance Use Mortality (NPSUM) and the Preventable Deaths Tracker (PDT) (https ...
Eman Mshari, Caroline S. Copeland, Georgia C. Richards   +2 more
wiley   +1 more source

Taiwan Controlled Substances Database

Journal of the Formosan Medical Association, 2022
New psychoactive substances (NPS) have increasingly been illegally synthesized and used around the world in recent years. Due to the large volume and the variety of NPS, most do not have sufficient information about their addictive potential and harmful ...
Yung-Wen Huang, Olivia A. Lin, Bo-Han Su, Ping-Han Hsieh, Ming-Yang Ho, Tien-Chueh Kuo, Yufeng Jane Tseng   +6 more
doaj   +1 more source

Herbal highs: review on psychoactive effects and neuropharmacology [PDF]

, 2017
Background: A new trend among users of new psychoactive substances’ the consumption of “herbal highs”: plant parts containing psychoactive substances.
Graziano, S, Orsolini, L, Pichini, S., Rotolo, Mc, Schifano, F, Tittarelli, R   +5 more
core   +1 more source

A Novel Workflow for Fast Elucidation of Drug Metabolites for Screening—Combining In Silico Metabolite Prediction With Trapped Ion Mobility QTOF‐MS

Drug Testing and Analysis, EarlyView.
UHPLC‐timsTOF‐MS with in silico prediction and automated annotation enabled rapid identification of quetiapine metabolites from pHLMs, facilitating their inclusion in targeted LC‐QTOF‐MS urine screening and improving biomarker detection for toxicological applications.
Annette Zschiesche, Birgit Schneider, Ilona Nordhorn, Carsten Baessmann, Laura M. Huppertz, Jürgen Kempf   +5 more
wiley   +1 more source

Synthetic cathinones related fatalities: an update [PDF]

, 2018
Synthetic cathinones, more commonly known as "bath salts", are synthetic drugs chemically related to cathinone, a psychostimulant found in the khat plant.
Busardò, F. P., Giorgetti, R., Marinelli, E., Pantano, F., Pichini, S., Zaami, S.   +5 more
core   +1 more source

Recreational Drug Use at a Music Festival: A Dual Approach Using Hair Biomarkers Analysis and Participant Self‐Reported Drug Use

Drug Testing and Analysis, EarlyView.
Combined self‐report and hair analysis in festival attendees (n = 249) revealed substantial discrepancies in drug use reporting, particularly for stimulants and dissociatives. This integrated approach enhances detection of poly‐drug use and provides a more reliable basis for monitoring and harm‐reduction strategies.
A. Y. Simão, T. Rosado, M. Barroso, M. Andraus, E. Gallardo   +4 more
wiley   +1 more source

Emergence of Novel Psychoactive Substance injecting associated with rapid rise in the population prevalence of hepatitis C virus [PDF]

, 2019
Background: Novel Psychoactive Substance (NPS) use has increased in recent years and generated significant concern within public health. People who inject drugs (PWID) are at increased risk of blood borne viruses, in particular Hepatitis C virus (HCV ...
Goldberg, David J., Hutchinson, Sharon J., McAuley, Andrew, Munro, Alison, Taylor, Avril, Yeung, Alan   +5 more
core   +3 more sources