Pharmacological Investigations of the Dissociative 'Legal Highs' Diphenidine, Methoxphenidine and Analogues. [PDF]
PLoS ONE, 2016 1,2-Diarylethylamines including lanicemine, lefetamine, and remacemide have clinical relevance in a range of therapeutic areas including pain management, epilepsy, neurodegenerative disease and depression.
Jason Wallach +9 more
doaj +10 more sources
'Legal highs' - what's in a name? [PDF]
BJPsych Bull, 2015 I wish to draw the reader's attention to our study, ‘Prevalence study of head shop drug usage in mental health’, published in this journal in February 2013. This is in light of recent publications focusing on the differential effects of cannabinoids on the development of psychosis,1 including the use of synthetic cannabinoids and an increased risk of ...
Lally J.
europepmc +5 more sources
Rapid Determination of the ‘Legal Highs’ 4-MMC and 4-MEC by Spectroelectrochemistry: Simultaneous Cyclic Voltammetry and In Situ Surface-Enhanced Raman Spectroscopy [PDF]
Sensors, 2021 The synthetic cathinones mephedrone (4-MMC) and 4-methylethcathinone (4-MEC) are two designer drugs that represent the rise and fall effect of this drug category within the stimulants market and are still available in several countries around the world ...
Jerson González-Hernández +7 more
doaj +2 more sources
Trends in Mortality From Novel Psychoactive Substances as “Legal Highs”: Gender Differences in Manner of Death and Implications for Risk Differences for Women [PDF]
Frontiers in Psychiatry, 2022 IntroductionThis study aimed to examine drug-related deaths in the UK in which novel psychoactive substances (NPS) are an implicated substance, and to focus on female deaths in comparison with male deaths.
Lucy Webb +4 more
doaj +2 more sources
Lysergic Acid Amide (LSA), an LSD Analog: Systematic Review of Pharmacological Effects, Adverse Outcomes, and Therapeutic Potentials [PDF]
PharmacyObjective: To systematically review the scientific literature on lysergic acid amide (LSA), focusing on its physical, neurobiological, and social effects, as well as its potential risks and therapeutic uses.
Paula S. C. C. Castro +7 more
doaj +2 more sources
The dilemma of new psychoactive substances: A growing threat [PDF]
Saudi Pharmaceutical Journal, 2023 New psychoactive substances (NPS) pose a major public threat and are a growing problem worldwide. They were designed to replace banned or controlled drugs while escaping quality control measures.
Hawraa Sameer Sajwani
doaj +2 more sources
Long-Lasting Cognitive and Physical Impairment After Recreational Use of the Semisynthetic Cannabinoid Hexahydrocannabinonyl (HHC-C9): A Case Report [PDF]
ReportsBackground and Clinical Significance: The recreational use of semisynthetic cannabinoids (SSCs) is increasing, and SSCs account for more than 40% of all new substances reported at the European level.
Nanna Reiter +5 more
doaj +2 more sources
The Dark Side of “Smart Drugs”: Cognitive Enhancement vs. Clinical Concerns [PDF]
ToxicsThe European Union Drugs Agency has emphasized the increasing difficulty in monitoring the drug market due to the emergence of new psychoactive substances, often marketed as legal highs.
Mariarosaria Ingegneri +6 more
doaj +2 more sources
"Air fresheners" as legal highs. [PDF]
Croat Med J, 2019 Bježančević M +2 more
europepmc +4 more sources
Legal highs and mental health [PDF]
, 2016 The use of novel psychoactive substances (NPS) or ‘legal highs’ is an emerging issue worldwide. There is rising concern around the risks of NPS and the detrimental effects on individuals’ mental health.
Solomon, Bernadette, Solomon, David
core +1 more source