Results 41 to 50 of about 2,978,655 (281)

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

Annals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold, Krzysztof W. Selmaj, Regina Berkovich, Jeffrey A. Cohen, Giancarlo Comi, Eva K. Havrdová, James K. Sheffield, Hetal Desai, Chun‐Yen Cheng, Jon V. Riolo, Andrew Thorpe, Erik DeBoer, Bruce A. C. Cree   +12 more
wiley   +1 more source

Dopalacze jako substancje szkodliwe dla zdrowia, stanowiące znamię przestępstwa z art. 165 § 1 pkt 2 k.k.

Problemy Prawa Karnego
The article analyses “legal highs” in the context of recognising this substance as a substance harmful to health, covered by the crime of causing a threat to the life or health of many people (Article 165 § 1 item 2 of the Penal Code).
Ryszard A. Stefański
doaj   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen, Stéphane Jean, Weihong Liu, Yihai Dai, Xinrong Fang, Xiaoqiang Wei, Shan Chen, Shiwei Song   +7 more
wiley   +1 more source

Forensic Analysis of Synthetic Cathinones on Nanomaterials-Based Platforms: Chemometric-Assisted Voltametric and UPLC-MS/MS Investigation

Nanomaterials, 2023
Synthetic cathinones (SCs) are a group of new psychoactive substances often referred to as “legal highs” or “bath salts”, being characterized by a dynamic change, new compounds continuously emerging on the market.
Ana-Maria Dragan, Bogdan George Feier, Mihaela Tertiș, Ede Bodoki, Florina Truta, Maria-Georgia Ștefan, Béla Kiss, Filip Van Durme, Karolien De Wael, Radu Oprean, Cecilia Cristea   +10 more
doaj   +1 more source

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon, Dana Olofson, Diana Anissian, Divyanshu Dubey, Eoin P. Flanagan, Max C. Herman, Sarosh R. Irani, Daniel H. Lachance, Maria A. Willrich, Sean Pittock, John R. Mills, Anastasia Zekeridou   +11 more
wiley   +1 more source

Monitoring risk behaviour in adolescent pupils regarding consumption of psychoactive substances

Annals of Agricultural and Environmental Medicine, 2017
Introduction Taking psychoactive substances constitutes a significant problem for Public Health, particularly in preventing drug abuse and addiction. Objectives To estimate the amount and incidence of drug consumption in middle and high school pupils ...
Paulina Wojtyła-Buciora, Aneta Klimberg, Lucyna Kapka-Skrzypczak, Jarosław Diatczyk, Monika Urbaniak, Ewa Ulatowska-Szostak, Tomasz Bołdowski, Andrzej Wojtyła, Jerzy T Marcinkowski   +8 more
doaj   +1 more source

Incidence of Intoxications in the Emergency Department of Galati Hospital with Examples of Cardiovascular Effects of MDMA Intoxication

Diagnostics, 2023
MDMA (3,4-methylenedioxymethamphetamine; commonly referred to as “Molly” or “ecstasy”) is a synthetic compound, structurally and pharmacologically similar to both amphetamines and mescaline.
Liliana Dragomir, Virginia Marina, Mihaela Anghele, Aurelian-Dumitrache Anghele, Cosmina Alina Moscu   +4 more
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Designer drug poisonings as a growing clinical problem

Journal of Education, Health and Sport, 2019
Introduction and purpose: Designer drugs also known as legal highs, research chemicals or herbal highs become more and more popular not only in Poland but also in other countries around the world.
Barbara Zofia Klatka, Anna Katarzyna Orzeł, Dominika Janeczko, Magdalena Hołowczuk, Michał Jerzy Terpiłowski, Michał Tchórz   +5 more
doaj   +3 more sources

New psycho-active substances: the legal procedure used in european union countries and Turkey

Psychiatry and Clinical Psychopharmacology, 2021
New psycho-active substances have recently begun to be substituted for narcotics as drugs of abuse. The main reason for this situation is that they are not included in the controlled substance list,despite the fact that they cause psychoactive effects ...
Faruk Asicioglu
doaj