Results 31 to 40 of about 282,476 (297)

Early and Late Infections in Newborns: Where Do We Stand? A Review

open access: yesPediatrics and Neonatology, 2016
Neonatal sepsis still represents an important cause of mortality and morbidity among infants. According to the onset, we can distinguish “early onset sepsis” when microbiological cultures positive for external pathogens come from newborns during the ...
Francesca Cortese   +7 more
doaj   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

Ontogenetic view on PIVKA-II in the development of prothrombin synthesis in infants

open access: yesPatologìâ, 2017
The aim of the research was to study the content of PIVKA-II in the blood serum as an integrative measure of latent vitamin K deficiency in breastfed infants aged from the birth to 6 months of life. Materials and methods.
O. G. Ivanko   +2 more
doaj   +1 more source

Distal Arthrogryposis in Newborn: Clinical Case

open access: yesВопросы современной педиатрии, 2020
Background. Arthrogryposis is severe congenital musculoskeletal disease with contractures of two or more joints of the lower and/or upper limbs and usually in combination with muscular hypo- or atrophy.Clinical Case Description. Child F. was hospitalized
Vasily P. Gavrilyuk   +3 more
doaj   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

Incidence of intrauterine infections in neonatal intensive care unit: a long-term epidemiological analysis

open access: yesФундаментальная и клиническая медицина, 2022
Aim. To improve epidemiological surveillance in the neonatal intensive care unit.Materials and Methods. We retrospectively examine case histories of 646 newborns delivered in Tyumen Perinatal Center and admitted to neonatal intensive care unit (310 with ...
O. M. Kuznetsova, A. N. Marchenko
doaj   +1 more source

Protein kinase FAM20C—when subcellular localization matters

open access: yesFEBS Letters, EarlyView.
FAM20C is a Golgi‐resident kinase that phosphorylates proteins along the entire secretory pathway. The presence of potential FAM20C substrates in the cytoplasm or nucleus raises the question of how the kinase and its substrates encounter each other. Protein kinases achieve signaling specificity through consensus sequence recognition and subcellular ...
Francesca Noventa, Mauro Salvi
wiley   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

open access: yesMolecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li   +12 more
wiley   +1 more source

EPSTEIN - BARR VIRAL INFECTION: MODERN SITUATION AND CLINICAL-EPIDEMIOLOGICAL FEATURES AMONG FERTILE WOMEN AND NEWBORNS

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2017
Aim. The investigate the current manifestations of the symptomatic and inapparent epidemic process of Epstein-Barr infection, as well as identification of its features in women of childbearing age and newborns. Materials and methods.
A. A. Asratyan   +7 more
doaj   +1 more source

Hypophosphatasia in the Newborn [PDF]

open access: yesArchives of Disease in Childhood, 1963
Archives of Disease in ...
Lapatsanis, P. D., Todd, R. M.
openaire   +4 more sources

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