Results 121 to 130 of about 57,232 (279)

ColdZyme® reduces viral load and upper respiratory tract infection duration and protects airway epithelia from infection with human rhinoviruses

open access: yesThe Journal of Physiology, Volume 603, Issue 6, Page 1483-1501, 15 March 2025.
Abstract figure legend These experiments provide robust evidence of the physiological mechanisms that explain the effects of ColdZyme, including protection against upper respiratory tract infection (URTI) and viral release from infected airway epithelial cells and better maintained cell integrity.
Glen Davison   +11 more
wiley   +1 more source

National consensus statement on opioid agonist treatment in custodial settings

open access: yesMedical Journal of Australia, Volume 222, Issue 5, Page 262-268, March 2025.
Abstract Introduction Opioid use and dependence are prevalent among incarcerated people, contributing to elevated rates of overdose and other harms in this population. Opioid agonist treatment (OAT) has been shown to be an effective intervention to mitigate these risks. However, challenges to health care implementation in the custodial sector result in
Jocelyn Chan   +7 more
wiley   +1 more source

Trust Erosion Framework for Organisational Responses to and Management of Global Emergencies

open access: yesJournal of Contingencies and Crisis Management, Volume 33, Issue 2, June 2025.
ABSTRACT In response to the societal crisis of trust widely documented by researchers and pollsters, this conceptual paper proposes a Trust Erosion Framework (TEF). By drawing analogies with the process of soil erosion, we postulate that the erosion of trust proceeds in stages: detachment, transportation and deposition.
LaShonda Eaddy   +5 more
wiley   +1 more source

The Super Enhancer‐Driven Long Noncoding RNA PRKCQ‐AS1 Promotes Neuroblastoma Tumorigenesis by Interacting With MSI2 Protein and Is Targetable by Small Molecule Compounds

open access: yesAdvanced Science, Volume 12, Issue 18, May 15, 2025.
PRKCQ‐AS1 is overexpressed due to transcriptional super‐enhancers. PRKCQ‐AS1 RNA forms a complex with MSI2 protein to induce BMX mRNA stabilization and overexpression, ERK protein phosphorylation and neuroblastoma cell proliferation. Compound NSC617570 blocks PRKCQ‐AS1 binding to MSI2, leading to BMX mRNA disassociation from MSI2 protein, BMX reduction,
Sujanna Mondal   +23 more
wiley   +1 more source

Serological Investigation of Newcastle Disease in Selected Districts of Buno Bedelle Zone, Ethiopia

open access: yesVeterinary Medicine: Research and Reports, 2021
Tamirat Mamo,1 Lama Yimer2 1Seyo District Livestock Development Office, Dembi Dollo, Ethiopia; 2School of Veterinary Medicine, Wollega University, Nekemte, EthiopiaCorrespondence: Lama YimerSchool of Veterinary Medicine, Wollega University, Nekemte ...
Mamo T, Yimer L
doaj  

Does the Use of Intravenous Immunoglobulin Improve Clinical Outcomes in Adults With Autoimmune Encephalitis? A Systematic Review

open access: yesBrain and Behavior, Volume 15, Issue 5, May 2025.
Evidence surrounding the use of IVIG in treating autoimmune encephalitis has yet to be evaluated and yet IVIG is used second line in this condition, after corticosteroids. IVIG is prone to donor shortages and therefore it would prove beneficial to establish whether this is an effective treatment; it can then be prioritised for this condition or others.
Anahat Kalra   +4 more
wiley   +1 more source

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