Results 131 to 140 of about 18,189,373 (355)
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
EXARC Journal, 2012 This interview with Dr. Errett Callahan began in the fall of 2010 during an 8-hour car ride from his home, Cliffside, in Lynchburg, Virginia to Gastonia, North Carolina where we both attended the first annual Reconstructive and Experimental Archaeology ...
Bill Schindler
doaj
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
‘Re-rolling’ a Mummy: an Experimental Spectacle at Manchester Museum
EXARC Journal, 2018 Ancient Egyptian animal mummies and votive statuettes were often wrapped in linen, concealing the contents and conferring sanctity to the remains. Mummy autopsies were commonplace in 19th century Europe, when ancient mummified bodies were unwrapped to ...
Lidija McKnight
doaj
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
The Itinerant Artist: Portraiting Early America Using Scissors, Soot and Beer
EXARC JournalHundreds of thousands of profile portraits known as silhouettes were created in the new United States in the first decade of 1800 alone. Since the 1990s, museum conservators have wondered how to best care for the materials of these objects in their ...
Lauren Muney
doaj
Hunting with Cane: Traditional Cherokee Blowguns and Darts
EXARC Journal, 2013 The Cherokee Indians were a large Southeastern tribe who occupied land in North Carolina, South Carolina, Georgia, Alabama, Tennessee and Virginia. During the Historic Period, the Cherokee were one of the Five Civilized Tribes and even had their own ...
Doug Meyer
doaj
Does cognition matter? Current pedagogical practice and the need for reform [PDF]
, 2016 Recent debate in the educational sphere highlights the continuing dilemma that is the creation and implementation of a true 21st century classroom in secondary schools across Australia.
Coleman, Clara +2 more
core +1 more source
Oncology LettersThe occurrence of acute myeloid leukemia (AML) with a simultaneous diagnosis of breast cancer (BC) is rarely reported in the literature. The present study reports the case of a 50-year-old female patient diagnosed with AML coexisting with metastatic BC.
Xing, Lina +5 more
openaire +2 more sources
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source