Results 161 to 170 of about 19,456,354 (363)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

EXARC visits Moscow

open access: yesEXARC Journal, 2017
Between the 1st to the 12th of June 2017, a huge festival called "Times and Epochs" (Времена и эпохи - Cобрание) was organized in Moscow. This was the occassion to gather participants not only from Russia, but also from many other countries, and ...
Milica Tapavički-Ilić, Artūrs Tomsons
doaj  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Bifurcation PCI Technique in the Era of Newer-Generation Drug-Eluting Stents: Insights from a Systematic Review and Meta-Analysis of Randomized Trials

open access: yesJournal of the American College of Cardiology, 2021
Tomohiro Fujisaki   +4 more
openaire   +2 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Book Review: Crafting in the World, Materiality in the Making by Burke and Spencer-Wood

open access: yesEXARC Journal, 2019
Archaeologists dream of books with comprehensive coverage that address specific gaps in knowledge and at the same time address theoretical issues and newer concerns about the nature of craft in a direct method.
Linda Anderson
doaj  

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

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