Results 181 to 190 of about 18,189,373 (355)

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Bifurcation PCI Technique in the Era of Newer-Generation Drug-Eluting Stents: Insights from a Systematic Review and Meta-Analysis of Randomized Trials

open access: yesJournal of the American College of Cardiology, 2021
Tomohiro Fujisaki   +4 more
openaire   +2 more sources

An Experimental Diachronic Exploration of Patination Methodology of Dark Patinated (Arsenical) Copper Alloys on Case Studies from the Eastern Mediterranean Bronze Age and Early Iron Age

open access: yesEXARC Journal, 2018
Artificially patinated copper alloys are found archaeologically in polychrome artefacts from the 19th century BC Egypt to historical and contemporary Japan. The unusual colour variations observed in these patinas, ranging from black to blue to purple, is
Marianne Talma
doaj  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Book Review: Experimentelle Archäologie in Europa, Bilanz 2011

open access: yesEXARC Journal, 2013
Bilanz 2011 once again supplies an exciting, diverse and interesting view into the world of experimental archaeology. Published by EXAR in cooperation with the Pfahlbaumuseum Unteruhldingen, Isensee Verlag, Oldenburg 2011, 270 pp, ISBN 978-3-89995-794 ...
Sina Lorbeer-Klausnitz
doaj  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Book Review: "Experiments Past" Edited by Jodi Reeves Flores and Roeland P. Paardekooper

open access: yesEXARC Journal, 2014
The publication in 1979 of the John Coles’ book Experimental Archaeology can be called the vademecum of the experimental archaeology. Many particular experiments have been published since then, such as A Bibliography of Replicative Experiments in ...
Clara Masriera i Esquerra
doaj  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

EXARC visits Moscow

open access: yesEXARC Journal, 2017
Between the 1st to the 12th of June 2017, a huge festival called "Times and Epochs" (Времена и эпохи - Cобрание) was organized in Moscow. This was the occassion to gather participants not only from Russia, but also from many other countries, and ...
Milica Tapavički-Ilić, Artūrs Tomsons
doaj  

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