Results 181 to 190 of about 19,456,354 (363)

Book Review: "Experiments Past" Edited by Jodi Reeves Flores and Roeland P. Paardekooper

open access: yesEXARC Journal, 2014
The publication in 1979 of the John Coles’ book Experimental Archaeology can be called the vademecum of the experimental archaeology. Many particular experiments have been published since then, such as A Bibliography of Replicative Experiments in ...
Clara Masriera i Esquerra
doaj  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Sherd Shatter Patterns Experiment

open access: yesEXARC Journal, 2017
In field archaeology, the importance of non-diagnostic sherds is often overlooked. This archaeological experiment suggests that archaeologists should take into greater consideration, contexts where sherds are found grouped together in close proximity ...
S. Evans, S. Barrera
doaj  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Book Review: Experimentelle Archäologie in Europa, Jahrbuch 2016

open access: yesEXARC Journal, 2017
The periodical "Experimentelle Archäologie" is issued by Gunter Schöbel and the "Europäische Vereinigung zur Förderung der experimentellen Archäologie", together with Pfahlbaumuseum Unteruhldingen from Germany. Issue no.
Milica Tapavički-Ilić
doaj  

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

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