Results 211 to 220 of about 19,456,354 (363)

New Era in Plant Alternative Splicing Analysis Enabled by Advances in High-Throughput Sequencing (HTS) Technologies [PDF]

, 2019
Renesh Bedre, Sonia Irigoyen, Ezequiel Petrillo, Kranthi K. Mandadi   +3 more
openalex   +1 more source

Editorial: 2021 European Society for Medical Oncology (ESMO) Recommendations on Laboratory Diagnostics for RET Gene Fusions and Mutations: A New Era in Targeted Therapy for RET-Altered Solid Tumors.

, 2021
Dinah V. Parums
openalex   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

TB far from elimination: an enduring reality in the southeast Asia region. [PDF]

Lancet Reg Health Southeast Asia
The Lancet Regional Health-Southeast Asia.
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Fabricated citations in the age of AI: A wake-up call for editors, reviewers, and authors. [PDF]

J Dent Sci
Liu H.
europepmc   +1 more source

On Robotic Surgery in Knee Arthroplasty: Beginning of a New Era

Arash Sherafat Vaziri, Sina Javidmehr, Fardis Vosoughi, Erfan Babaei Nejad, Kaveh Same   +4 more
openalex   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Editorial: Non-insulin pharmacotherapies for the treatment of type 2 diabetes and obesity - old and new players. [PDF]

Front Clin Diabetes Healthc
Patoulias D, Muzurović E, Rizzo M.
europepmc   +1 more source

Study on the Current Situation and Countermeasures of China’s Aging Population in the New Era—Learning from Japan’s Experience [PDF]

园园 陈
openalex   +1 more source