Results 51 to 60 of about 29,480 (254)
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
The Best Way of Preserving Something is to Educate about it - Educational Centres in South Africa
This article aims to show the kind of issues South- African archaeologists have, working with public archaeology. A past that was segregated earlier should now be shared, but sharing a common past includes alternative perspectives on history and ...
Frauke Sontberg
doaj
Breathing Life Sustainably - An Abandoned Settlement to an Open-Air Museum Twah Longwar
Twah Longwar is an abandoned settlement located in the State of Meghalaya in North-East India. It is located enroute to one of the world's rainiest places on earth – Mawsynram.
Naphibahun Lyngdoh
doaj
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Replication of a Maori Ethnographic Textile Hem Border Pattern
Replication of archaeological and ethnographic Māori textiles, under the direction of customary knowledge and previous practical experience, can provide a more nuanced understanding of the manufacture of taonga (treasures) made from fibre materials.
Lisa McKendry
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
This paper takes the form of a critical analysis of archaeological experiments using spinning tools. The archaeological experiments regarding whorl weight and wool spinning of the Tools and Textiles – Texts and Contexts project, through the Danish ...
Tracy P. Hudson
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
This year’s Association of European Open Air Museums (AEOM) Biannual Conference 2019 took place at multiple sites in Poland, over four days in late August.
Peter Inker
doaj

