Results 101 to 110 of about 4,421 (228)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Reinventing EXARC, a Discussion between Members
EXARC Journal, 2016 At the Annual General Meeting in Leiden (NL) in March 2016, about 25 EXARC members discussed future strategies for EXARC. We intend to collect opinions from members throughout 2016 and present a plan at the Annual General Meeting in 2017.
Roeland P Paardekooper
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Book Review: Heritage Tourism Destinations by Maria D Alvarez (et al.)
EXARC Journal, 2016 This book is a follow-up from the first Hospitality, Tourism and Heritage International Conference, held in Istanbul, Turkey from the 6th to the-7th November 2014. It is wonderful that these papers were published only two years later. This book’s goal is
Roeland P Paardekooper
doaj
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
How to Run a Reenactment - Introduction to Reenactments and Reenactors, Part 1
EXARC Journal, 2019 Reenactments, meaning special events that use outside costumed interpreters, are a great way for sites to engage visitors and host memorable programs that build a following. Planning and executing a reenactment can be a daunting challenge for a site that
Deb Fuller
doaj
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Navigating the intelligence revolution: transforming cardiovascular care through AI-driven innovation. [PDF]
Open HeartTang Y, Zhao K, Zhao S.
europepmc +1 more source
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
The New Era of "Diabetes Prevention, Care and Management": Precision Tools, Predictive Models and New Technologies. [PDF]
Diabetes Metab Syndr ObesCarafa A, Maddaloni E.
europepmc +1 more source