Results 91 to 100 of about 4,421 (228)

Experimental Approaches to Student Success

open access: yesEXARC Journal, 2018
An undergraduate student who hopes to secure meaningful work or pursue graduate studies needs to have excellent grades. This is true for all disciplines, but especially for niche fields like archaeology.
Tim Messner
doaj  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Taking Archaeological Concepts outside the Social Science Class in Indian Schools

open access: yesEXARC Journal, 2019
In Indian classrooms, social sciences receive disproportionately less attention than natural sciences and mathematics (Dahiya, 2003; Lall and House, 2005; Roy, 2017).
Smriti Haricharan
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Conference Review: Summa Summarum - Experimental Archaeology in the Balkans

open access: yesEXARC Journal, 2019
From May 30 to June 1, the 42nd conference of the Serbian Archeological Society was held in Negotin (Serbia). The session "Summa summarum - experimental archaeology in the Balkans" was co-organised with EXARC.
Ivan Semyan, Spyros Bakas
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The Museum World’s Convention in Kyoto

open access: yesEXARC Journal, 2019
ICOM is the international council of museums with over 40,000 members. Every three years, ICOM organises a large convention for museum professional; this year the 25th ICOM general conference was held in Kyoto, Japan.
Roeland P Paardekooper
doaj  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Historical Techniques: Cold Gilding

open access: yesEXARC Journal, 2012
An historal technique of goldplating, described in 18th century literature, was reproduced. This cold-plating technique uses salts of gold, produced by dissolving gold in aqua regia. these salts are then rubbed onto a silver surfaces.
Michiel Langeveld
doaj  

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