Results 91 to 100 of about 5,397 (276)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

“Likely to be eaten by a Grue” – the relevance of text games in the modern era

open access: yes, 2013
Spurred on by the success of Tim Schafer and Brian Fargo in crowd-sourcing funds for their newest projects, I look to reinvigorate interest in the humble text game.
Heron, M.
core  

Fenomena Facebook: Keterlibatan Teknologi Komunikasi dalam Perkembangan Komunikasi Manusia

open access: yes, 2017
The development of communication always connect with the technology development of human being. Concepts and theories which establish in a period will be change in the time where technology dominated human being. The newest technology of internet web 2.0
Agustina Zubair
core   +1 more source

Discussion: The Concept of Authenticity in Collections of Open-Air Museums

open access: yesEXARC Journal, 2021
How is it possible that if you go into an arts museum, the ceramics you see may be made yesterday and may be a valued and legitimate part of the museum collection, while in open-air museums, a similar object may be produced by a master craftsperson ...
For the authors see the article
doaj  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Time travel – a Great Method to Strengthen Cooperation between Museums and Schools. The Experience of Nationwide Time Travels in Estonia.

open access: yesEXARC Journal
In Estonia the method of Time Travel has been used for more than 10 years. While the first time travels were conducted in a rather casual and modest way, a change took place in 2016 with the first nationwide project.
Kaari Siemer
doaj  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Conference Review: ACTION! Museums in the Climate Crisis, NEMO 2023

open access: yesEXARC Journal
The NEMO European Museum Conference 2023: and… ACTION! Museums in the climate crisis took place in Lahti, Finland from 19-21 November. Almost 300 museum professionals from all over Europe took part, listening, discussing, and being inspired by a variety ...
Julia Heeb
doaj  

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Fold-the-Interfashionality: A Dialogue between Modernity and Tradition in the Era of AI [PDF]

open access: yes, 2019
Mixing new technology with traditional craft, PhD researchers from the Royal College of Art (RCA) in London, Mingjing Lin and Tsai-Chun Huang, utilise the newest developments in 3D printing, algorithm-based modelling and traditional Eastern pleating to ...
Huang, Tsai-chun, Lin, Mingjing
core  

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