Results 71 to 80 of about 1,643,238 (264)

The Rearrangement of the Archaeological Museum of Arcevia: Aiming to Improve Accessibility

open access: yesEXARC Journal, 2023
The Marche region in central Italy hosts quite a number of archaeological museums, containing a wide range of specimens and collections that cover a time span from the Palaeolithic onwards.
Mauro Fiorentini
doaj  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Book Review: Experimental Archaeology: Making, Understanding, Story-telling by Souyoudzoglou-Haywood and O’Sullivan (eds)

open access: yesEXARC Journal, 2020
The volume contains the proceedings of a two-day workshop on Experimental Archaeology, hosted by the Irish Institute of Hellenic Studies at Athens (Greece) in October 2017. As stated in the Introduction (O’Sullivan, Souyoudzoglou-Haywood, pp.
Francesca Tomei
doaj  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Experimental Bonfirings of Pottery with Camel Dung Fuel, Jordan, July 2018

open access: yesEXARC Journal, 2019
The objective of this series of experimental pottery firings with camel dung fuel was to isolate the function of this fuel type within the context of a simple mode of pottery firing for data applicable to studies of ancient pottery manufacture.
Maria-Louise Sidoroff
doaj  

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Best practices and innovative capacity development approaches in ARD programmes of ERA-ARD consortium members: Draft compilation of National Contribution

open access: yes, 2007
In the framework of the European Research Area for Agricultural Research for Development (ERA-ARD) project, a survey of innovative approaches in capacity development (CD) was undertaken. All Consortium members were asked to describe innovative approaches
Giger, Markus, Kaufmann, Manfred
core  

120 Years of Strategies and Experiences in Educational and Handicraft Skills

open access: yesEXARC Journal, 2013
Report on a Study-visit to Skansen Open-Air Museum,Stockholm / Sweden, Summer 2013. One aim of the five year EU-funded Culture Project OpenArch is to encourage cooperation between archaeological open-air museums in Europe and ethnological open-air ...
Rüdiger Kelm
doaj  

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