Results 61 to 70 of about 1,643,238 (264)

Conference Review: ACTION! Museums in the Climate Crisis, NEMO 2023

open access: yesEXARC Journal
The NEMO European Museum Conference 2023: and… ACTION! Museums in the climate crisis took place in Lahti, Finland from 19-21 November. Almost 300 museum professionals from all over Europe took part, listening, discussing, and being inspired by a variety ...
Julia Heeb
doaj  

X-Ray Tomography and Infrared Spectrometry for the Analysis Of Throwing Sticks and Boomerangs

open access: yesEXARC Journal, 2019
Throwing sticks, including boomerangs as a subclass, are prehistoric objects as old as humanity. They have endured on many continents in different forms, uses, and traditions of manufacture.
Luc Bordes
doaj  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

How to make Yours one of the Good presentations

open access: yesEXARC Journal, 2016
“The two words 'information' and 'communication' are often used interchangeably, but they signify quite different things. Information is giving out; communication is getting through”.
Neil Peterson
doaj  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Celebrating International Museum Day 2023... Internationally

open access: yesEXARC Journal
In order to celebrate International Museum Day 2023, I strived to make a change in a personal format to mark the occasion as being as international as possible.
Aija Héloïse Pince
doaj  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Book Review: The Routledge Handbook of Reenactment Studies by Agnew, Lamb and Tomann (eds)

open access: yesEXARC Journal, 2020
Re-enactment studies are booming, just like re-enactment, living history and role play are. This handbook, therefore, is a good introduction for those interested in the more academic aspects of re-enactment. However, as is often the case with an academic-
Roeland Paardekooper
doaj  

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