Results 101 to 110 of about 1,973,449 (292)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
News Won’t Find Me? Exploring Inequalities in Social Media News Use With Tracking Data
International Journal of Communication, 2022 The rise of news content on social media has been accompanied by a hope that people with lower socioeconomic status and less interest in political affairs would be “accidentally” exposed to news.
Lisa Merten +4 more
doaj
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Transformation and transcendence – reforming news production in the convergent media era
Trans/Form/AçãoThe present-day networked media ecosystem is distinctly characterized by convergence. Recently, media convergence has experienced rapidly progress both in theoretical circles and in practical applications, and convergence development has inevitably ...
Zhi Li, Yinchang Chen
doaj +1 more source
Ranking News-Quality Multimedia
, 2018 News editors need to find the photos that best illustrate a news piece and fulfill news-media quality standards, while being pressed to also find the most recent photos of live events. Recently, it became common to use social-media content in the context
Arapakis Ioannis +3 more
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Contextualization: A Path to Chinese Traditional News Media’s Integration Into Social Media
Media and CommunicationMeyrowitz’s media context theory proposes that new media and their contexts will lead to new behaviors. This article adopts media context theory as a framework and utilizes a textual analysis approach to analyze what Meyrowitz termed middle region ...
Difan Guo, Haiyan Wang, Jinghong Xu
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Social Networking and Online Videos Take Off: Internet's Broader Role in Campaign 2008 [PDF]
, 2008 Presents findings from a survey on presidential campaign news and political communication, with a focus on the Internet's growing role, by news source, generation, sites, and party.
core
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source