Results 111 to 120 of about 1,973,449 (292)

Reading between the lines : is news media in Fiji supporting or challenging gender stereotypes? : a frame analysis of local news media coverage of violence against women during the 16 Days of Activism against Gender-based Violence campaign of 2017 [PDF]

open access: yes, 2018
Violence against women is recognised as a global public health issue and an obstacle to development, as ending it is inextricably linked with achieving gender equality.
Van Baaren, Ellie
core  

Strategic news frames and public policy debates: Press and television news coverage of the euro in the UK [PDF]

open access: yes
There is growing concern amongst observers of the media that news coverage of politics has moved away from a focus on issues, and instead towards political strategy.
Jackson, Dan
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Nobody Wants to Eat Them Alive:” Ethical Dilemmas and Dual Media Narratives on Domestic Rabbits as Pets and Commodity [PDF]

open access: yes, 2013
Using semiotic analysis, this study explores changes occurring in the societal perception of rabbits as farm animals as juxtaposed to their increasing popularity as domestic companions.
Lowe, Brian, Torosyan, Gayane F.
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

New Media, Legacy Media and Misperceptions Regarding Sourcing [PDF]

open access: yesKOME: An International Journal of Pure Communication Inquiry, 2017
Resource dependence theory and related theories of management suggest online-only news media may displace legacy news media, but until that happens the two systems are likely to be dependent on the same resource: news.
Stan Diel
doaj  

The Effects of Media Coverage on Mass Shootings in the United States [PDF]

open access: yes, 2018
This paper discusses the effects media coverage and media portrayal have on mass shootings in the United States. As the occurrences of mass shootings in the United States have increased, the depiction of these events through news outlets, media stories ...
Chen, Lisa
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

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