Results 111 to 120 of about 19,825,415 (296)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Political Economy of News Media and Journalism

open access: yes
The political economy of news media and journalism critically examines the structures, processes, and democratic role of journalism within society. It is focused on the power relations that shape the production, distribution, and consumption of online ...
Salamon, Errol
core   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Inside the news: challenges and aspirations of women journalists in Asia and the Pacific [PDF]

open access: yes, 2015
There are more women media professionals than ever in many countries across Asia-Pacific, but they still represent only three out of 10 newsroom staff, often earn less than their male counterparts and are subject to sexual harassment, while struggling to
UN Women
core  

When Readers Do Not Fight Falsehood: An Exploration of Factors Influencing the Perceived Realism of False News on International Disputes

open access: yesSocial Sciences
This study examines the effects of misleading news—one type of false information presented by news media in the U.S. and China—in the context of international disputes.
Mingxiao Sui, Yunjuan Luo, Newly Paul
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

News Events and Price Movements. Price Effects of Economic and Non-Economic Publications in the News Media [PDF]

open access: yes
Numerous empirical studies have demonstrated that asset prices react rapidly, if at all, to news published in the mass media. In many cases, the information has been discounted and prices have already moved upon primary publication through news wires ...
Thomas Schuster
core  

Credibilidad de los medios: un análisis bivariado de las opiniones de los españoles. Media credibility: a bivariate analysis of the Spanish views

open access: yesRevista Mediterránea de Comunicación, 2012
Credibility is a central topic in the debate about the news media. Several reasons justify its study such as the implication on the news media quality or the possible association with people’s media consume. This paper examines the Spanish public opinion
Pedro FARIAS-BATLLE, Sergio ROSES
doaj  

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