Results 81 to 90 of about 1,963,105 (289)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Exploring News Media Literacy and its Dimensions
Diversitas JournalOur civic and democratic participation mostly relies on the quality of the news we consume. In this study, news media literacy dimensions are explored. It looks at how intrinsic motivation, news media skepticism, and media locus of control relate to one ...
Jerrel Panayo, Cleoffer Tolentino
doaj +1 more source
News Coverage of the 2016 National Conventions: Negative News, Lacking Context [PDF]
, 2016 A new report from Harvard Kennedy School's Shorenstein Center on Media, Politics and Public Policy analyzes news coverage of the 2016 Republican and Democratic national conventions, and whether this coverage, which was overwhelmingly negative, best ...
Thomas E. Patterson
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Scrutinizing News Media Cooperation in Facebook and Twitter
IEEE AccessIn recent times, news media avail oneself of online social media platforms for news promotion, sharing, and commentary to a large extent mainly in Twitter, Facebook, and Reddit.
Praboda Rajapaksha +2 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Italy in the Australian news media, 2005-2012 [PDF]
, 2013 Presents a systematic analysis of the coverage of Italian matters in the Australian news media in the period 2005-2012. Executive summary The study presents a systematic analysis of the coverage of Italian matters in the Australian news media in the ...
Franco Papandrea +2 more
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Comunicação e SociedadeDigitalization has led to a crisis in news media and an upheaval in media ownership. A research concern has been that the motives driving media owners will shift from financial and public service to overtly political and ideological.
Mark Blach-Ørsten +3 more
doaj +1 more source