Results 91 to 100 of about 3,662,984 (294)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Topics and issues of musical education in the news
Aula, 2010 In music education, practice is essential. The new generations of music educators are beginning to understand that while there are many different ways of thinking about music education, is imperative to warn about the polarization of educational thought ...
Violeta HEMSY DE GAINZA
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
PLoS ONEEvery day thousands of news are published on the web and filtering tools can be used to extract knowledge on specific topics. The categorization of news into a predefined set of topics is a subject widely studied in the literature, however, most works ...
Klaifer Garcia +2 more
doaj +1 more source
Discovering opinion leaders for medical topics using news articles
Journal of Biomedical Semantics, 2012 Background Rapid identification of subject experts for medical topics helps in improving the implementation of discoveries by speeding the time to market drugs and aiding in clinical trial recruitment, etc.
Jonnalagadda Siddhartha +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Chicago Summer Institute 2013 - Deconstructing TV News
, 2013 Deconstructing TV News Powerpoint Slides HandoutA PDF file of the PowerPoint presentation for the lecture on "Deconstructing TV News." Topics include: advantages and disadvantages of TV news, how to deconstruct TV news, reliability of sources, I'M ...
Stony Brook University. School of Journalism. Center for News Literacy.
core
Newport News & Hampton Railway, Gas & Electric Company
, 1914 This is a twenty-Nine page booklet describing the major historical attractions in Newport News, Virginia and Hampton, Virginia.
Newport News & Hampton Railway, Gas & Electric Company
core +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source