Results 121 to 130 of about 1,460,723 (393)
Short barcodes for next generation sequencing. [PDF]
PLoS ONE, 2013 We consider the design and evaluation of short barcodes, with a length between six and eight nucleotides, used for parallel sequencing on platforms where substitution errors dominate.
Katharina Mir +3 more
doaj +1 more source
Identities for second order recurrence sequences [PDF]
arXiv, 2018 We derive several identities for arbitrary homogeneous second order recurrence sequences with constant coefficients. The results are then applied to present a unified study of six well known integer sequences, namely the Fibonacci sequence, the sequence of Lucas numbers, the Jacobsthal sequence, the Jacobsthal-Lucas sequence, the Pell sequence and the ...
arxiv
VarDict: a novel and versatile variant caller for next-generation sequencing in cancer research
Nucleic Acids Research, 2016 Accurate variant calling in next generation sequencing (NGS) is critical to understand cancer genomes better. Here we present VarDict, a novel and versatile variant caller for both DNA- and RNA-sequencing data.
Z. Lai +9 more
semanticscholar +1 more source
WaveCNV: allele-specific copy number alterations in primary tumors and xenograft models from next-generation sequencing. [PDF]
, 2013 MotivationCopy number variations (CNVs) are a major source of genomic variability and are especially significant in cancer. Until recently microarray technologies have been used to characterize CNVs in genomes.
Ali, Johar +11 more
core +3 more sources
miRNA‐29 regulates epidermal and mesenchymal functions in skin repair
FEBS Letters, EarlyView.miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan +10 more
wiley +1 more source
FEBS Letters, EarlyView.We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring +6 more
wiley +1 more source
Journal of Neuroinflammation, 2023 Introduction Zika virus (ZIKV) caused an outbreak in Brazil, in 2015, being associated to microcephaly. ZIKV has a strong neurotropism leading to death of infected cells in different brain regions, including the hippocampus, a major site for neurogenesis.
Marina da Silva Oliveira +8 more
doaj +1 more source
Next‐generation sequencing for mitochondrial disorders [PDF]
British Journal of Pharmacology, 2014 A great deal of our understanding of mitochondrial function has come from studies of inherited mitochondrial diseases, but still majority of the patients lack molecular diagnosis. Furthermore, effective treatments for mitochondrial disorders do not exist.
Anu Suomalainen +2 more
openaire +3 more sources
nCk sequences and their difference sequences [PDF]
arXiv, 2015 A nCk sequence is a sequence of n-bit numbers with k bits set. Given such a sequence C, the difference sequence D of C is subject to certain regularities that make it possible to generate D in 2|C| time, and, hence, to generate C in 3|C| time.
arxiv
FEBS Letters, EarlyView.Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek +15 more
wiley +1 more source