Results 121 to 130 of about 149,500 (265)

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

Molecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park, Sang Shin Lee, Shihyun Kim, Yeonjun Lee, Gyeonwon Park, Jung Oh Kim, Jongho Choi   +6 more
wiley   +1 more source

HLA Genotyping using Next Generation Sequencing

Romanian Journal of Internal Medicine, 2016
From an oncological perspective, the second most common malignancies in children are brain tumors. Despite the recent therapeutic breakthroughs in this field, concerning surgery, radiotherapy and chemotherapy alike, some cases still have poor outcomes in
Lucan C., Pop Laura-Ancuta, Florian A., Pileczki Valentina, Petrushev B., Dima Delia, Frinc Ioana, Berindan-Neagoe Ioana, Irimie A., Berce C., Florian I.-S., Bojan Anca, Tomuleasa C.   +12 more
doaj   +1 more source

Next-Generation Sequencing of Cancer Genomes: Back to the Future [PDF]

, 2009
Matthew J. Walter, Timothy A. Graubert, John F. DiPersio, Elaine R. Mardis, Richard K. Wilson, Timothy J. Ley   +5 more
openalex   +1 more source

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

Molecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad, Caterina Miro, Annarita Nappi, Francesco Del Giudice, Annunziata Gaetana Cicatiello, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Melania Murolo, Emery Di Cicco, Federico Capone, Ciro Imbimbo, Monica Dentice, Felice Crocetto   +13 more
wiley   +1 more source

On sequency-complete and sequency-ordered matrices [PDF]

arXiv
The concept of sequency holds a fundamental significance in signal analysis using Walsh basis functions. In this study, we closely examine the concept of sequency and explore the properties of sequency-complete and sequency-ordered matrices. We obtain results on cardinalities of sets containing sequency-complete and sequency-ordered matrices of ...
arxiv  

Composition inverses of the variations of the Baum-Sweet sequence [PDF]

arXiv, 2018
Studying and comparing arithmetic properties of a given automatic sequence and the sequence of coefficients of the composition inverse of the associated formal power series (the formal inverse of that sequence) is an interesting problem. This problem was studied before for the Thue-Morse sequence.
arxiv  

Next-generation sequencing technologies and their implications for crop genetics and breeding [PDF]

, 2009
Rajeev K. Varshney, Spurthi N. Nayak, Gregory D. May, Scott A. Jackson   +3 more
openalex   +1 more source

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

Molecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran, Clarence Yapp, Gregory J. Baker, Johanna Beyer, Young Hwan Chang, Allison L. Creason, Robert Krueger, Jeremy Muhlich, Nathan Heath Patterson, Kevin Sidak, Damir Sudar, Adam J. Taylor, Luke Ternes, Jakob Troidl, Xie Yubin, Artem Sokolov, Darren R. Tyson   +16 more
wiley   +1 more source

Opacity complexity of automatic sequences. The general case [PDF]

arXiv
In this work we introduce a new notion called opacity complexity to measure the complexity of automatic sequences. We study basic properties of this notion, and exhibit an algorithm to compute it. As applications, we compute the opacity complexity of some well-known automatic sequences, including in particular constant sequences, purely periodic ...
arxiv  

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

Molecular Oncology, EarlyView.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang, Anna Schritz, Nikolai Goncharenko, Guy Berchem   +3 more
wiley   +1 more source