Results 271 to 280 of about 1,460,723 (393)

Application of Metagenomic Next-Generation Sequencing in HIV-Infected Patients with Bloodstream Infections. [PDF]

Infect Drug Resist
Liu H, Xu T, Fu H, Dai B, Xie Y.
europepmc   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

Identification of factors required for meristem function in Arabidopsis using a novel next generation sequencing fast forward genetics approach [PDF]

, 2011
Michal Mokrý, Isaäc J. Nijman, Anja van Dijken, René Benjamins, Renze Heidstra, Ben Scheres, Edwin Cuppen   +6 more
openalex   +1 more source

Next-Generation Sequencing in Oncology-A Guiding Compass for Targeted Therapy and Emerging Applications. [PDF]

Int J Mol Sci
Galeș LN, Păun MA, Butnariu I, Simion L, Manolescu LSC, Trifănescu OG, Anghel RM.   +6 more
europepmc   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Genotype and SNP calling from next-generation sequencing data [PDF]

, 2011
Rasmus Nielsen, Joshua Paul, Anders Albrechtsen, Yun S. Song   +3 more
openalex   +1 more source

Real-World Data: Implementation and Outcomes of Next-Generation Sequencing in the MENA Region. [PDF]

Diagnostics (Basel)
Mahfouz R, Abou Zeidane R, Diab T, Tarhini A, Sbaity E, Kazarian H, El Zibaoui Y, Naji NS, Barake M, Assi HI.   +9 more
europepmc   +1 more source

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

Molecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci, Izzet Akiva, Yavuz Hakan Ozon, Hakan Berkil, Huseyin Karadayi, Omer Dizdar, Suayib Yalcin   +6 more
wiley   +1 more source

Diversity Arrays Technology (DArT) and next-generation sequencing combined: genome-wide, high throughput, highly informative genotyping for molecular breeding of Eucalyptus [PDF]

, 2011
Carolina Sansaloni, César Daniel Petroli, Damian Jaccoud, Jason Carling, Frank Detering, Dário Grattapaglia, Andrzej Kilian   +6 more
openalex   +1 more source

Next-generation peptide sequencing [PDF]

Nature Methods, 2018
openaire   +2 more sources