Results 41 to 50 of about 1,444,385 (351)
Defining Culture Conditions for the Hidden Nitrite-Oxidizing Bacterium Nitrolancea
Frontiers in Microbiology, 2020 Nitrification is a key process for N-removal in engineered and natural environments, but recent findings of novel nitrifying microorganisms with surprising features revealed that our knowledge of this functional guild is still incomplete.
Eva Spieck +8 more
doaj +1 more source
Target enrichment using parallel nanoliter quantitative PCR amplification [PDF]
, 2014 Background: Next generation targeted resequencing is replacing Sanger sequencing at high pace in routine genetic diagnosis. The need for well validated, high quality enrichment platforms to complement the bench-top next generation sequencing devices is ...
De Wilde, Bram +7 more
core +2 more sources
A new targeted CFTR mutation panel based on next-generation sequencing technology [PDF]
, 2017 Searching for mutations in the cystic fibrosis transmembrane conductance regulator gene (CFTR) is a key step in the diagnosis of and neonatal and carrier screening for cystic fibrosis (CF), and it has implications for prognosis and personalized therapy ...
Alberti, Luisella +10 more
core +2 more sources
TATuP – Zeitschrift für Technikfolgenabschätzung in Theorie und Praxis, 2021 Next Generation Sequencing led to major knowledge gains in the molecular life sciences. But the new technology provides data that pose new challenges to both science and society.
Elsbeth Bösl, Stefanie Samida
doaj +1 more source
Human Genetics, 2017 The Human Gene Mutation Database (HGMD®) constitutes a comprehensive collection of published germline mutations in nuclear genes that underlie, or are closely associated with human inherited disease.
P. Stenson +8 more
semanticscholar +1 more source
A Comprehensive Review of Performance of Next-Generation Sequencing Platforms
BioMed Research International, 2022 Background Next-generation sequencing methods have been developed and proposed to investigate any query in genomics or clinical activity involving DNA.
M. T. Pervez +5 more
semanticscholar +1 more source
Pyrosequencing/Sanger Plant Genome Assembly (Limitations, Problems And Solutions) - On The Way To Cucumber (Cucumis sativus L. cv. Borszczagowski) Draft Genome Sequence Publishing [PDF]
, 2010 Genome sequencing give us an opportunity to broaden the range and improve the quality of omics studies. New sequencing technologies make it possible to achieve the sequencing reads fast and cheap.
Rafal Woycicki, Zbigniew Przybecki
core +2 more sources
AIMS Microbiology, 2018 Background: The deep-sea mussels Bathymodiolus azoricus (Bivalvia: Mytilidae) are the dominant macrofauna subsisting at the hydrothermal vents site Menez Gwen in the Mid-Atlantic Ridge (MAR).
Inês Barros +7 more
doaj +1 more source
Clustering and Alignment of Polymorphic Sequences for HLA-DRB1 Genotyping [PDF]
, 2013 Located on Chromosome 6p21, classical human leukocyte antigen genes are highly polymorphic. HLA alleles associate with a variety of phenotypes, such as narcolepsy, autoimmunity, as well as immunologic response to infectious disease.
A McKenna +35 more
core +3 more sources
Suppressing gain-of-function proteins via CRISPR/Cas9 system in SCA1 cells
Scientific Reports, 2022 SCAs are autosomal dominant neurodegenerative disorders caused by a gain-of-function protein with toxic activities, containing an expanded polyQ tract in the coding region.
Mariangela Pappadà +14 more
doaj +1 more source