Results 41 to 50 of about 1,460,723 (393)

BamView: visualizing and interpretation of next-generation sequencing read alignments. [PDF]

, 2012
So-called next-generation sequencing (NGS) has provided the ability to sequence on a massive scale at low cost, enabling biologists to perform powerful experiments and gain insight into biological processes.
Berriman, Matthew, Carver, Tim, Harris, Simon R., McQuillan, Jacqueline A., Otto, Thomas D., Parkhill, Julian   +5 more
core   +1 more source

NGS QC Toolkit: A Toolkit for Quality Control of Next Generation Sequencing Data

PLoS ONE, 2012
Next generation sequencing (NGS) technologies provide a high-throughput means to generate large amount of sequence data. However, quality control (QC) of sequence data generated from these technologies is extremely important for meaningful downstream ...
Ravi K. Patel, Mukesh Jain
semanticscholar   +1 more source

Neuroinflammation regulates the balance between hippocampal neuron death and neurogenesis in an ex vivo model of thiamine deficiency

Journal of Neuroinflammation, 2022
Background Thiamine (vitamin B1) is a cofactor for enzymes of central energy metabolism and its deficiency (TD) impairs oxidative phosphorylation, increases oxidative stress, and activates inflammatory processes that can lead to neurodegeneration ...
Larissa M. G. Cassiano, Marina S. Oliveira, Jeanne Pioline, Anna C. M. Salim, Roney S. Coimbra   +4 more
doaj   +1 more source

Next-Generation Sequencing: The Race Is On [PDF]

Cell, 2008
The $1000 genome may still be years away, but with the arrival of next-generation sequencing (NGS) technologies that are much faster and cheaper than the traditional Sanger method, large-scale sequencing of hundreds or even thousands of human genomes is fast becoming reality.
openaire   +2 more sources

Reconstructing mitochondrial genomes directly from genomic next-generation sequencing reads—a baiting and iterative mapping approach

Nucleic Acids Research, 2013
We present an in silico approach for the reconstruction of complete mitochondrial genomes of non-model organisms directly from next-generation sequencing (NGS) data—mitochondrial baiting and iterative mapping (MITObim). The method is straightforward even
C. Hahn, L. Bachmann, Bastien Chevreux
semanticscholar   +1 more source

Diagnostic applications of next generation sequencing: working towards quality standards [PDF]

, 2012
Over the past 6 years, next generation sequencing (NGS) has been established as a valuable high-throughput method for research in molecular genetics and has successfully been employed in the identification of rare and common genetic variations. All major
Adey, Andrea Gehring, Anna Benet-Pagès, Bainbridge, Bentley, Carsten Bergmann, Clark, Clement, Ding, Dohm, Gerlinger, Gregory, Greif, Greif, Hanno Jörn Bolz, Hanns-Georg Klein, Harismendy, Ina Vogl, Jiang, Johansson, Kaimo Hirv, Kalari, Klaus H. Metzeler, Koboldt, Li, Lister, Loman, Mamanova, Manfred Stuhrmann, Mardis, Marius Kuhn, Mertes, Meyerson, Minoche, Nakamura, Philipp A. Greif, Robinson, Rothberg, Saskia Biskup, Sebastian H. Eck, Shendure, Stefan Kotschote, Stratton   +42 more
core   +1 more source

Defining Culture Conditions for the Hidden Nitrite-Oxidizing Bacterium Nitrolancea

Frontiers in Microbiology, 2020
Nitrification is a key process for N-removal in engineered and natural environments, but recent findings of novel nitrifying microorganisms with surprising features revealed that our knowledge of this functional guild is still incomplete.
Eva Spieck, Katharina Sass, Sabine Keuter, Sophia Hirschmann, Michael Spohn, Daniela Indenbirken, Linnea F. M. Kop, Sebastian Lücker, Alejandra Giaveno   +8 more
doaj   +1 more source

A Comprehensive Review of Performance of Next-Generation Sequencing Platforms

BioMed Research International, 2022
Background Next-generation sequencing methods have been developed and proposed to investigate any query in genomics or clinical activity involving DNA.
M. T. Pervez, M. J. Hasnain, S. H. Abbas, M. Moustafa, Naeem Aslam, Syed Shah Muhammad Shah   +5 more
semanticscholar   +1 more source

Evaluation of experimental design and computational parameter choices affecting analyses of ChIP-seq and RNA-seq data in undomesticated poplar trees. [PDF]

, 2014
BackgroundOne of the great advantages of next generation sequencing is the ability to generate large genomic datasets for virtually all species, including non-model organisms.
Filkov, Vladimir, Groover, Andrew, Liu, Lijun, Missirian, Victor, Zinkgraf, Matthew   +4 more
core   +2 more sources

On the Gap-sum and Gap-product Sequences of Integer Sequences [PDF]

arXiv, 2021
In this note, we explore two families of sequences associated to a suitable integer sequence: the gap-sum sequence and the gap-product sequence. These are the sums and the products of consecutive numbers not in the original sequence. We give closed forms for both, in terms of the original sequence, and in the case of Horadam sequences, we find the ...
arxiv