Results 11 to 20 of about 524,928 (262)
TATuP – Zeitschrift für Technikfolgenabschätzung in Theorie und Praxis, 2021 Next Generation Sequencing led to major knowledge gains in the molecular life sciences. But the new technology provides data that pose new challenges to both science and society.
Elsbeth Bösl, Stefanie Samida
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Indian Journal of Medical and Paediatric Oncology, 2020 Guruprasad Bhat, Amit Kumar Jain
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Next generation sequencing in cytology [PDF]
Cytopathology, 2021 AbstractThe application of next generation sequencing (NGS) technology to cytological samples has significantly modified molecular cytopathology practice. Cytological samples represent a valid source of high‐quality DNA for NGS analysis, especially for predicting patients' response to targeted treatments and for refining the risk of malignancy in ...
Pisapia, Pasquale +11 more
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Next-generation sequencing demands next-generation phenotyping [PDF]
Human Mutation, 2012 Next-generation sequencing (NGS) is the most powerful diagnostic tool since the roentgenogram. NGS will facilitate diagnosis on a massive scale, allowing interrogation of all genes in a single assay. It has been suggested that NGS will decrease the need for phenotyping in general and medical geneticists in particular. We argue that NGS will shift focus
Hennekam, Raoul C. M. +1 more
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Next-generation sequencing [PDF]
Breast Cancer Research, 2009 Next-generation sequencing (also known as massively parallel sequencing) technologies are revolutionising our ability to characterise cancers at the genomic, transcriptomic and epigenetic levels. Cataloguing all mutations, copy number aberrations and somatic rearrangements in an entire cancer genome at base pair resolution can now be performed in a ...
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NGSNGS: next-generation simulator for next-generation sequencing data [PDF]
Bioinformatics, 2023 AbstractSummaryWith the rapid expansion of the capabilities of the DNA sequencers throughout the different sequencing generations, the quantity of generated data has likewise increased. This evolution has also led to new bioinformatical methods, for which in silico data have become crucial when verifying the accuracy of a model or the robustness of a ...
Rasmus Amund Henriksen +2 more
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Single-cell gene expression analysis of cryopreserved equine bronchoalveolar cells
Frontiers in Immunology, 2022 The transcriptomic profile of a cell population can now be studied at the cellular level using single-cell mRNA sequencing (scRNA-seq). This novel technique provides the unprecedented opportunity to explore the cellular composition of the bronchoalveolar
Sophie E. Sage +6 more
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Viruses, 2021 Rotarix® vaccine was implemented nationwide in Zambia in 2013. In this study, four unusual strains collected in the post-vaccine period were subjected to whole genome sequencing and analysis.
Wairimu M. Maringa +7 more
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Viruses, 2021 Children in low-and middle-income countries, including Rwanda, experience a greater burden of rotavirus disease relative to developed countries. Evolutionary mechanisms leading to multiple reassortant rotavirus strains have been documented over time ...
Sebotsana Rasebotsa +11 more
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Bioinformatics and Next- generation Sequencing [PDF]
Klinicka onkologie, 2015 Next-generation sequencing technologies are currently well-established in the research field and progressively find their way towards clinical applications. Sequencers produce vast amounts of data and therefore bioinformatics methods are needed for processing.
A, Krejčí, P, Müller, B, Vojtěšek
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