Results 11 to 20 of about 5,172,921 (307)
TATuP – Zeitschrift für Technikfolgenabschätzung in Theorie und Praxis, 2021 Next Generation Sequencing led to major knowledge gains in the molecular life sciences. But the new technology provides data that pose new challenges to both science and society.
Elsbeth Bösl, Stefanie Samida
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Indian Journal of Medical and Paediatric Oncology, 2020 Guruprasad Bhat, Amit Kumar Jain
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Next-generation sequencing [PDF]
Breast Cancer Research, 2009 Next-generation sequencing (also known as massively parallel sequencing) technologies are revolutionising our ability to characterise cancers at the genomic, transcriptomic and epigenetic levels. Cataloguing all mutations, copy number aberrations and somatic rearrangements in an entire cancer genome at base pair resolution can now be performed in a ...
Atsushi, Toyoda, Asao, Fujiyama
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Next-Generation Sequencing [PDF]
Journal of Biomedicine and Biotechnology, 2010 It has been widely appreciated that the genome sequence is shaping the future biomedical research. The genome sequence provides a general framework for assembling fragmentary DNA information into landscape of biological structure and function [1]. The rapid advances in DNA sequencing technology are revolutionizing biomedical research.
Xiong, Momiao +3 more
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Next-generation sequencing demands next-generation phenotyping [PDF]
Human Mutation, 2012 Next-generation sequencing (NGS) is the most powerful diagnostic tool since the roentgenogram. NGS will facilitate diagnosis on a massive scale, allowing interrogation of all genes in a single assay. It has been suggested that NGS will decrease the need for phenotyping in general and medical geneticists in particular. We argue that NGS will shift focus
Hennekam, Raoul C. M. +1 more
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Next generation sequencing in cytology [PDF]
Cytopathology, 2021 AbstractThe application of next generation sequencing (NGS) technology to cytological samples has significantly modified molecular cytopathology practice. Cytological samples represent a valid source of high‐quality DNA for NGS analysis, especially for predicting patients' response to targeted treatments and for refining the risk of malignancy in ...
Pisapia, Pasquale +11 more
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Diagnostic applications of next generation sequencing: working towards quality standards [PDF]
, 2012 Over the past 6 years, next generation sequencing (NGS) has been established as a valuable high-throughput method for research in molecular genetics and has successfully been employed in the identification of rare and common genetic variations. All major
Klein, Hanns-Georg +27 more
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RADSeq: next-generation population genetics [PDF]
, 2010 Next-generation sequencing technologies are making a substantial impact on many areas of biology, including the analysis of genetic diversity in populations.
Davey, John L +3 more
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Comprehensive Detection of Candidate Pathogens in the Lower Respiratory Tract of Pediatric Patients With Unexpected Cardiopulmonary Deterioration Using Next-Generation Sequencing [PDF]
, 2020 Objectives: Next-generation sequencing has been applied to the investigation of microorganisms in several clinical settings. We investigated the infectious etiologies in respiratory specimens from pediatric patients with unexpected cardiopulmonary ...
Suzuki, Takako +21 more
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NGSNGS: next-generation simulator for next-generation sequencing data [PDF]
Bioinformatics, 2023 AbstractSummaryWith the rapid expansion of the capabilities of the DNA sequencers throughout the different sequencing generations, the quantity of generated data has likewise increased. This evolution has also led to new bioinformatical methods, for which in silico data have become crucial when verifying the accuracy of a model or the robustness of a ...
Rasmus Amund Henriksen +2 more
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