Results 31 to 40 of about 5,172,921 (307)

From cheek swabs to consensus sequences : an A to Z protocol for high-throughput DNA sequencing of complete human mitochondrial genomes [PDF]

open access: yes, 2014
Background: Next-generation DNA sequencing (NGS) technologies have made huge impacts in many fields of biological research, but especially in evolutionary biology. One area where NGS has shown potential is for high-throughput sequencing of complete mtDNA
Matisoo-Smith, Elizabeth A   +83 more
core   +1 more source

Defining Culture Conditions for the Hidden Nitrite-Oxidizing Bacterium Nitrolancea

open access: yesFrontiers in Microbiology, 2020
Nitrification is a key process for N-removal in engineered and natural environments, but recent findings of novel nitrifying microorganisms with surprising features revealed that our knowledge of this functional guild is still incomplete.
Eva Spieck   +8 more
doaj   +1 more source

Neuroinflammation regulates the balance between hippocampal neuron death and neurogenesis in an ex vivo model of thiamine deficiency

open access: yesJournal of Neuroinflammation, 2022
Background Thiamine (vitamin B1) is a cofactor for enzymes of central energy metabolism and its deficiency (TD) impairs oxidative phosphorylation, increases oxidative stress, and activates inflammatory processes that can lead to neurodegeneration ...
Larissa M. G. Cassiano   +4 more
doaj   +1 more source

The Evolution of Post-Vaccine G8P[4] Group a Rotavirus Strains in Rwanda; Notable Variance at the Neutralization Epitope Sites

open access: yesPathogens, 2023
Africa has a high level of genetic diversity of rotavirus strains, which is suggested to be a possible reason contributing to the suboptimal effectiveness of rotavirus vaccines in this region.
Peter N. Mwangi   +13 more
doaj   +1 more source

Next generation sequencing technologies for next generation plant breeding [PDF]

open access: yesFrontiers in Plant Science, 2014
As a term, “next generation plant breeding” is increasingly becoming popular in crop breeding programmes, conferences, scientific fora and social media (Schnable, 2013). Being a frontier area of crop science and business, it is gaining considerable interest among scientific community and policymakers and funds flow from entrepreneurs and research ...
SOHAM eRAY, PRATIK eSATYA
doaj   +3 more sources

Next-generation sequencing primers.

open access: yes, 2023
List of primers used for next-generation sequencing of gDNA extracted from pooled CRISPR activation screen samples. Primers were adapted from Sanson and colleagues [5]. (DOCX)
Lipin Loo (462678)   +22 more
core   +1 more source

Targeted genetic testing for familial hypercholesterolaemia using next generation sequencing:a population-based study [PDF]

open access: yes, 2014
BACKGROUND: Familial hypercholesterolaemia (FH) is a common Mendelian condition which, untreated, results in premature coronary heart disease. An estimated 88% of FH cases are undiagnosed in the UK.
Soutar, Anne K.   +39 more
core   +2 more sources

Next-Generation Sequencing Technologies [PDF]

open access: yesCold Spring Harbor Perspectives in Medicine, 2018
Although DNA and RNA sequencing has a history spanning five decades, large-scale massively parallel sequencing, or next-generation sequencing (NGS), has only been commercially available for about 10 years. Nonetheless, the meteoric increase in sequencing throughput with NGS has dramatically changed our understanding of our genome and ourselves ...
McCombie, W Richard   +2 more
openaire   +4 more sources

Next-Generation Sequencing Panel Test in Myeloid Neoplasms and Evaluation with the Clinical Results

open access: yes, 2022
Objective: Myeloid malignancies are heterogeneous disorders due to defective hematopoiesis and myeloid differentiation of hematopoietic stem/progenitor cell. The molecular landscape of the diseases is complex.
Gulden Sincan   +5 more
core   +1 more source

Advancements in Next-Generation Sequencing [PDF]

open access: yesAnnual Review of Genomics and Human Genetics, 2016
The term next-generation sequencing is almost a decade old, but it remains the colloquial way to describe highly parallel or high-output sequencing methods that produce data at or beyond the genome scale. Since the introduction of these technologies, the number of applications and methods that leverage the power of genome-scale sequencing has ...
Shawn E, Levy, Richard M, Myers
openaire   +2 more sources

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