Results 21 to 30 of about 523,633 (260)
Viruses, 2021 Rotarix® vaccine was implemented nationwide in Zambia in 2013. In this study, four unusual strains collected in the post-vaccine period were subjected to whole genome sequencing and analysis.
Wairimu M. Maringa +7 more
doaj +1 more source
Next-generation sequencing in dermatology
Frontiers in Medicine, 2023 Over the past decade, Next-Generation Sequencing (NGS) has advanced our understanding, diagnosis, and management of several areas within dermatology. NGS has emerged as a powerful tool for diagnosing genetic diseases of the skin, improving upon traditional PCR-based techniques limited by significant genetic heterogeneity associated with these disorders.
Andrew D. King +5 more
openaire +3 more sources
Viruses, 2021 Children in low-and middle-income countries, including Rwanda, experience a greater burden of rotavirus disease relative to developed countries. Evolutionary mechanisms leading to multiple reassortant rotavirus strains have been documented over time ...
Sebotsana Rasebotsa +11 more
doaj +1 more source
Seasonal dynamics of DNA and RNA viral bioaerosol communities in a daycare center
Microbiome, 2019 Background Viruses play an important role in ecosystems, including the built environment (BE). While numerous studies have characterized bacterial and fungal microbiomes in the BE, few have focused on the viral microbiome (virome).
Aaron J. Prussin +6 more
doaj +1 more source
Viruses, 2023 Although the introduction of rotavirus vaccines has substantially contributed to the reduction in rotavirus morbidity and mortality, concerns persist about the re-emergence of variant strains that might alter vaccine effectiveness in the long term.
Robyn-Lee Potgieter +11 more
doaj +1 more source
Defining Culture Conditions for the Hidden Nitrite-Oxidizing Bacterium Nitrolancea
Frontiers in Microbiology, 2020 Nitrification is a key process for N-removal in engineered and natural environments, but recent findings of novel nitrifying microorganisms with surprising features revealed that our knowledge of this functional guild is still incomplete.
Eva Spieck +8 more
doaj +1 more source
Journal of Neuroinflammation, 2022 Background Thiamine (vitamin B1) is a cofactor for enzymes of central energy metabolism and its deficiency (TD) impairs oxidative phosphorylation, increases oxidative stress, and activates inflammatory processes that can lead to neurodegeneration ...
Larissa M. G. Cassiano +4 more
doaj +1 more source
Next-Generation Sequencing Technologies [PDF]
Cold Spring Harbor Perspectives in Medicine, 2018 Although DNA and RNA sequencing has a history spanning five decades, large-scale massively parallel sequencing, or next-generation sequencing (NGS), has only been commercially available for about 10 years. Nonetheless, the meteoric increase in sequencing throughput with NGS has dramatically changed our understanding of our genome and ourselves ...
McCombie, W Richard +2 more
openaire +4 more sources
Advancements in Next-Generation Sequencing [PDF]
Annual Review of Genomics and Human Genetics, 2016 The term next-generation sequencing is almost a decade old, but it remains the colloquial way to describe highly parallel or high-output sequencing methods that produce data at or beyond the genome scale. Since the introduction of these technologies, the number of applications and methods that leverage the power of genome-scale sequencing has ...
Shawn E, Levy, Richard M, Myers
openaire +2 more sources
Pathogens, 2023 Africa has a high level of genetic diversity of rotavirus strains, which is suggested to be a possible reason contributing to the suboptimal effectiveness of rotavirus vaccines in this region.
Peter N. Mwangi +13 more
doaj +1 more source