Results 221 to 230 of about 963,855 (274)

Evaluation of false positive and false negative errors in targeted next generation sequencing. [PDF]

Genome Biol
Moon Y, Kim YH, Kim JK, Hong CH, Kang EK, Choi HW, Lee DE, Kim TM, Heo SG, Han N, Hong KM.   +10 more
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Germline targeted next-generation sequencing in patients with adrenal incidentalomas. [PDF]

Front Endocrinol (Lausanne)
Messina E, Inglesi A, Puglisi S, Barač Nekić A, Morelli V, Alessi Y, Zibar Tomsic K, Palmieri S, Tomaiuolo P, Grosso E, Ferraù F, Chiodini I, Kastelan D, Pia A, Scatolini M, Reimondo G, Terzolo M.   +16 more
europepmc   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Next generation sequencing as a panacea for antibiotic susceptibility testing: yea or nay? [PDF]

Front Public Health
van Belkum A.
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Profiling of microbes associated with chronic irreversible pulpitis using metagenomic next-generation sequencing. [PDF]

BMC Oral Health
Shetty P, Bhat R, Padavu S, Rai P, B KK, Shetty S.   +5 more
europepmc   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Urinary microRNAs for the non-invasive diagnosis of endometriosis identified by next-generation sequencing and machine learning. [PDF]

Reprod Biol Endocrinol
Kupec T, Wittenborn J, Kuo CC, Najjari L, Senger R, Meyer-Wilmes P, Stickeler E, Maurer J.   +7 more
europepmc   +1 more source