Curcumin Blocks Cytokine-Mediated NF-κB Activation and Proinflammatory Gene Expression by Inhibiting Inhibitory Factor I-κB Kinase Activity [PDF]
, 1999 Christian Jobin +6 more
openalex +1 more source
The p65 subunit of NF-κB regulates IκB by two distinct mechanisms
, 1993 Transcription factor NF-κB (p50/p65) is generally localized to the cytoplasm by its inhibitor IκB. Overproduced IκB, free from NF-κB, is rapidly degraded. Overexpression of p65 increases endogenous IκB protein in both carcinoma and lymphoid cells by two mechanisms: protein stabilization and increased transcription of IκB mRNA.
Scott, Martin L. +4 more
openaire +2 more sources
Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules
Advanced Materials Interfaces, EarlyView.This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania +2 more
wiley +1 more source
Progress and Application of Multifunctional Hydrogel in Radioactive Skin Injury
Advanced Materials Interfaces, EarlyView.This review examines healing challenges in radiation‐wound injuries, where ionizing radiation impairs immune and tissue repair processes. Hydrogels, with their biocompatibility, antimicrobial properties, and drug delivery capabilities, present a transformative solution. It compares hydrogel efficacy in radiation‐induced versus common wounds, highlights
Xinyue Cui +5 more
wiley +1 more source
Exacerbation of Damage and Altered NF-κB Activation in Mice Lacking Tumor Necrosis Factor Receptors after Traumatic Brain Injury [PDF]
, 1999 Patrick G. Sullivan +6 more
openalex +1 more source
BP/MoS₂ Van Der Waals Heterojunctions for Self‐Powered Photoconduction
Advanced Optical Materials, EarlyView.A multilayer black phosphorus (BP)/monolayer MoS₂ vertical heterostructure is investigated using four‐probe measurements. The device exhibits rectifying behavior, dominant n‐type transport, low contact resistance, and an interface barrier of 68 meV.
Adolfo Mazzotti +9 more
wiley +1 more source
Induction of NF-κB Activity during Haloperidol-Induced Oxidative Toxicity in Clonal Hippocampal Cells: Suppression of NF-κB and Neuroprotection by Antioxidants [PDF]
, 1998 Anke Post, Herta Flor, Christian Behl
openalex +1 more source
Advanced Photonics Research, EarlyView.This study demonstrates a label‐free optical method to monitor cells using a terahertz metasurface‐based biosensing platform. The obtained terahertz signal change for the cell‐contained nanoslots before and after external stimulus is analyzed in terms of transmittance and frequency shift, dynamically representing the cell apoptosis process.
Yeeun Roh +4 more
wiley +1 more source
Journal of Pharmacological Sciences, 2012 The nuclear factor-κB (NF-κB) transcription factors control many physiological processes including inflammation, immunity, and apoptosis. In our search for NF-κB inhibitors from natural resources, we identified yangonin from Piper methysticum as an ...
Juan Ma +10 more
doaj
Tumor Necrosis Factor α Induces the Adenovirus Early 3 Promoter by Activation of NF-κB [PDF]
, 1996 François Deryckère +1 more
openalex +1 more source