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T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
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NETs drive myocardial fibrosis in hypertension via an NF-κB/ferroptosis axis. [PDF]
Front ImmunolTu Q +6 more
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NF-κB in inflammation and cancer. [PDF]
Cell Mol ImmunolMao H, Zhao X, Sun SC.
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Targeting CCNB1 Repressed Cartilage Degradation Induced by Inflammation Through NF-κB Pathway in Osteoarthritis. [PDF]
J Histochem CytochemLi H, Qiao Y, Ding M, Liu Y.
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Heterogeneous NF-κB activation and enhancer features shape transcription in Drosophila immunity. [PDF]
Biophys JNawar N, Rits E, Cohen LB, Wunderlich Z.
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Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways. [PDF]
Mol Med RepWang YH +7 more
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The expression and significance of NF-κB, MMP1, and MMP2 in rats with abdominal aortic aneurysm
Cellular and Molecular Biology, 2020This study aimed to investigate the expression and significance of NF-κB, matrix metal protein1 (MMP1), and matrix metal protein2 (MMP2) in rats with abdominal aortic aneurysm (AAA). 48 Wistar rats were collected, then they were divided into an experiment group and a control group (n=24).
Zhilei, Xie, Tao, Fang
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