Results 1 to 10 of about 188,422 (163)
Cell survival from chemotherapy depends on NF-kappaB transcriptional up-regulation of coenzyme Q biosynthesis. [PDF]
PLoS ONE, 2009 BACKGROUND: Coenzyme Q (CoQ) is a lipophilic antioxidant that is synthesized by a mitochondrial complex integrated by at least ten nuclear encoded COQ gene products.
Gloria Brea-Calvo +4 more
doaj +1 more source
Role of NF-kappaB in thyroid cancer.
Molecular and cellular endocrinology, 2009 Thyroid cancer is the most common neoplasia of the endocrine system and accounts for approximately 1% of all newly diagnosed cancer cases. Its incidence has rapidly grown over the past few decades. Although most thyroid carcinomas are of the well-differentiated papillary histology, and respond well to treatment with surgical resection followed by ...
PACIFICO, FRANCESCO MARIA +1 more
openaire +6 more sources
Cutaneous lymphomas – an update
Histopathology, EarlyView.Primary cutaneous lymphomas and lymphoproliferative disorders are defined by integrated clinical, histopathological, immunophenotypic and genetic features as diagnostic criteria also in the 5th edition of the WHO classification of haematolymphoid tumors.
Werner Kempf, Christina Mitteldorf
wiley +1 more source
Constitutive activation of NF-kappa B is not sufficient to disturb normal steady-state hematopoiesis
Haematologica, 2006 Since nuclear factor-kappaB (NF-kappaB) is frequently activated in acute myeloid leukemia, we questioned whether active NF-kappaB can affect the cellular properties of cord blood CD34+ cells.
H Schepers +3 more
doaj
Tumor suppressor CYLD acts as a negative regulator for non-typeable Haemophilus influenza-induced inflammation in the middle ear and lung of mice. [PDF]
PLoS ONE, 2007 Non-typeable Haemophilus influenza (NTHi) is an important human pathogen causing respiratory tract infections in both adults and children. NTHi infections are characterized by inflammation, which is mainly mediated by nuclear transcription factor kappaB (
Jae Hyang Lim +9 more
doaj +1 more source
Immunity, Inflammation and Disease, Volume 14, Issue 9, September 2026.ABSTRACT Ethnopharmacological Relevance According to Chinese medicine theory, chronic glomerulonephritis (CGN) is characterized by dampness‐heat and blood stasis. Danggui Buxue Decoction (DBD) has shown good efficacy in the treatment of diseases associated with qi deficiency and blood stasis (such as CGN).
Qiao Liu +5 more
wiley +1 more source
Bmi-1 promotes the aggressiveness of glioma via activating the NF-kappaB/MMP-9 signaling pathway
BMC Cancer, 2012 Background The prognosis of human glioma is poor, and the highly invasive nature of the disease represents a major impediment to current therapeutic modalities. The oncoprotein B-cell-specific Moloney murine leukemia virus integration site 1 protein (Bmi-
Jiang Lili +6 more
doaj +1 more source
Ser276 phosphorylation of NF-kB p65 by MSK1 controls SCF expression in inflammation. [PDF]
PLoS ONE, 2009 Transcription of the mast cell growth factor SCF (stem cell factor) is upregulated in inflammatory conditions, and this is dependent upon NF-kappaB, as well as the MAP kinases p38 and ERK activation.
Laurent Reber +3 more
doaj +1 more source
Protein Posttranslational Modifications in Immunity: Molecular Mechanisms and Therapeutic Targets
MedComm, Volume 7, Issue 9, September 2026.Protein posttranslational modifications, including phosphorylation, ubiquitination, SUMOylation, acetylation, methylation, glycosylation, and other new types, dynamically regulate antigen presentation and recognition, immune signal transduction, antibody production and class switching, immune contraction, immune memory establishment, as well as immune ...
Yuxing Yao +10 more
wiley +1 more source
Brain Pathology, Volume 36, Issue 5, September 2026.We report the clinical and genetic features of an institutional cohort of primary adult gliosarcomas compared to glioblastoma. We performed spatial whole‐transcriptome analysis on glial and sarcomatous regions of four cases to compare gene expression profiles and validated differential protein expression for two markers in tissue sections.
Matthew D. Wood +6 more
wiley +1 more source