Results 291 to 300 of about 456,853 (317)

Effects of miR-7 on Hcy-induced rat cerebral arterial vascular smooth muscle cell proliferation, migration and inflammatory factor expression by targeting MMP-14 to regulate TLR4/NF-κB signaling pathway

Cellular and Molecular Biology, 2020
The current research aimed to investigate the effect of miR-7 targeting matrix metalloproteinase 14 (MMP-14) on homocysteine (Hcy)-induced rat cerebral artery vascular smooth muscle cells (VSMCs) proliferation, migration and inflammatory factor expression and its possible mechanism.
Hongdan, Ma, Lei, Wang, Wen, Lv, Zheng, Lv   +3 more
openaire   +2 more sources

miR-675 promotes disease progression of non-small cell lung cancer via activating NF-κB signaling pathway

Cellular and Molecular Biology, 2017
Non-small cell lung cancer (NSCLC) is a major type of lung cancer significantly affected human life. Current studies have revealed potential role of miR-675 in the etiology of lung cancer. Therefore, in this study, we aimed to investigate the role of miR-675 in NSCLC cell line.
Y, Feng, C, Yang, D, Hu, X, Wang, X, Liu
openaire   +2 more sources

Phillygenin inhibits LPS-induced activation and inflammation of LX2 cells by TLR4/MyD88/NF-κB signaling pathway.

Journal of Ethnopharmacology, 2020
ETHNOPHARMACOLOGICAL RELEVANCE The traditional Chinese medicine Forsythiae Fructus is the dried fruit of Forsythia suspensa (Thunb.) Vahl. It is commonly used to clear heat and detoxify, reduce swelling and disperse knot, and evacuate wind and heat ...
Naihua Hu, Cheng Wang, X. Dai, Mengting Zhou, Lihong Gong, Lingyuan Yu, Cheng Peng, Yunxia Li   +7 more
semanticscholar   +1 more source

Lipopolysaccharide pretreatment inhibits oxidative stress-induced endothelial progenitor cell apoptosis via a TLR4-mediated PI3K/Akt/ NF-κB p65 signaling pathway

Cellular and Molecular Biology, 2019
Endothelial progenitor cells (EPCs) improve neovascularization and endothelium regeneration. Transplantation with EPCs is a therapeutic strategy for the treatment of ischemic diseases. However, the transplanted EPCs are susceptible to adverse environments such as hypoxia, inflammation and oxidative stress.
Meihui, Wang, Liang, Xia, Guosheng, Fu
openaire   +2 more sources

Curcumin inhibits cigarette smoke-induced inflammation via modulating the PPARγ-NF-κB signaling pathway.

Food & Function, 2019
Peroxisome proliferator-activated receptor gamma (PPARγ), a ligand-activated nuclear hormone receptor, is considered to be a potential target for the anti-inflammatory treatment of COPD, and its anti-inflammatory efficacy is likely related to the ...
Qiuping Li, Jing Sun, N. Mohammadtursun, Jinfeng Wu, Jingcheng Dong, Lulu Li   +5 more
semanticscholar   +1 more source

Activation by IKKα of a Second, Evolutionary Conserved, NF-κB Signaling Pathway

Science, 2001
U. Senftleben, Yixue Cao, G. Xiao, F. Greten, G. Krähn, G. Bonizzi, Yi Chen, Yinling Hu, A. Fong, Shao-Cong Sun, M. Karin   +10 more
semanticscholar   +1 more source

AKR7A3 suppresses tumorigenicity and chemoresistance in hepatocellular carcinoma through attenuation of ERK, c-Jun and NF-κB signaling pathways

Journal of Liver, 2017
openaire   +1 more source

The adenosine pathway in immuno-oncology

Nature Reviews Clinical Oncology, 2020
Bertrand Allard, Laurence Buisseret, John Stagg   +2 more
exaly  

The cGAS–STING pathway as a therapeutic target in inflammatory diseases

Nature Reviews Immunology, 2021
Alexiane Decout, Andrea Ablasser
exaly  

Lineage plasticity in cancer: a shared pathway of therapeutic resistance

Nature Reviews Clinical Oncology, 2020
Helena A Yu, Dana Pe'er, Charles L Sawyers   +2 more
exaly