Results 171 to 180 of about 271,508 (291)

NF-kappa B in colorectal cancer

open access: yes, 2013
Colorectal cancer (CRC) is a leading cause of morbidity and mortality worldwide, responsible for more than half a million deaths annually. CRC is a multistep process that entails the accumulation of genetic/epigenetic aberrations, which lead to the simultaneous failure of protective mechanisms and the activation of tumorigenic pathways.
Vaiopoulos, Aristeidis G.   +2 more
openaire   +1 more source

Magnetic Fe3O4 nanoparticles and chemotherapy agents interact synergistically to induce apoptosis in lymphoma cells

open access: yesInternational Journal of Nanomedicine, 2010
Hongmei Jing1, Jing Wang1, Ping Yang1, Xiaoyan Ke1, Guohua Xia2, Baoan Chen21Department of Hematology and Lymphoma Research Center, Peking University Third Hospital, Beijing, People’s Republic of China; 2Department of Hematology, The Affiliated
Hongmei Jing   +3 more
doaj  

Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis

open access: yesBMEMat, EarlyView.
This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang   +6 more
wiley   +1 more source

[NF-kappa B and inflammatory intestinal diseases].

open access: yesRevista espanola de enfermedades digestivas, 1998
The chronic inflammatory bowel diseases (IBD), such as Crohn's disease (CD) and ulcerative colitis (UC), are multifactorial pathologies. There is overwhelming evidence that genetic factors play a pivotal role in the predisposition to suffer from IBD.
M P, Nosti-Escanilla, A S, Peña
openaire   +1 more source

Calcium retinoate nanoparticle mediated microglial polarization to regulate inflammatory microenvironment for therapy of neuroinflammatory disease

open access: yesBMEMat, EarlyView.
A nano‐drug based on retinoic acid and calcium is developed, which can be rapily endocytosed by microglia and decomposed into small molecule/ion storms in lysosomes. This nano‐drug regulates microglial phenotype switching from M1 to M2 while indirectly guiding neuronal differentiation of endogenous neural stem cells, thereby ameliorating ...
Shuo Zhang   +13 more
wiley   +1 more source

Gold-quercetin nanoparticles prevent metabolic endotoxemia-induced kidney injury by regulating TLR4/NF-kB signaling and Nrf2 pathway in high fat diet fed mice

open access: yesInternational Journal of Nanomedicine, 2017
Min-Xuan Xu,1,2,* Ming Wang,3,* Wei-Wei Yang4 1Chongqing Key Laboratory of Medicinal Resources in the Three Gorges Reservoir Region, School of Biological and Chemical Engineering, Chongqing University of Education, Chongqing, 2College of Engineering and
Xu MX, Wang M, Yang WW
doaj  

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

open access: yesBMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan   +8 more
wiley   +1 more source

Amelioration of collagen-induced arthritis using antigen-loaded dendritic cells modified with NF-κB decoy oligodeoxynucleotides

open access: yesDrug Design, Development and Therapy, 2017
Hongmei Jiang,1 Henggui Hu,2 Yali Zhang,1 Ping Yue,3 Lichang Ning,1 Yan Zhou,1 Ping Shi,1 Rui Yuan1 1School of Clinical Laboratory Science, Guizhou Medical University, Guiyang, Guizhou, 2Department of Clinical Laboratory, The Third Hospital Subsidiary ...
Jiang HM   +7 more
doaj  

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