Results 191 to 200 of about 99,051 (206)

The crystal structure of the IkappaBalpha/NF-kappaB complex reveals mechanisms of NF-kappaB inactivation.

Cell, 1999
IkappaBalpha regulates the transcription factor NF-kappaB through the formation of stable IkappaBalpha/NF-kappaB complexes. Prior to induction, IkappaBalpha retains NF-kappaB in the cytoplasm until the NF-kappaB activation signal is received. After activation, NF-kappaB is removed from gene promoters through association with nuclear IkappaBalpha ...
T, Huxford, D B, Huang, S, Malek, G, Ghosh   +3 more
openaire   +1 more source

Shared principles in NF-kappaB signaling.

Cell, 2008
The transcription factor NF-kappaB has served as a standard for inducible transcription factors for more than 20 years. The numerous stimuli that activate NF-kappaB, and the large number of genes regulated by NF-kappaB, ensure that this transcription factor is still the subject of intense research.
Matthew S, Hayden, Sankar, Ghosh
openaire   +1 more source

NF-kappaB and rheumatic diseases.

Endocrine, metabolic & immune disorders drug targets, 2007
NF-kappaB is an inducible transcription factor that is controlled by the signal activation cascades. NF-kappaB controls a number of genes involved in immuno-inflammatory responses, cell cycle progression, inhibition of apoptosis, and cell adhesion, thus promoting chronic inflammatory responses.
openaire   +1 more source

The NF-kappaB regulatory network.

Cardiovascular toxicology, 2007
Nuclear factor (NF)-kappaB is a family of seven structurally related transcription factors that play a central role in cardiovascular growth, stress response, and inflammation by controlling gene network expression. Although the NF- kappaB subunits are ubiquitously expressed, their actions are regulated in a celltype and stimulus-specific manner ...
openaire   +1 more source

Oncogenic activation of NF-kappaB.

Cold Spring Harbor perspectives in biology, 2010
Recent genetic evidence has established a pathogenetic role for NF-kappaB signaling in cancer. NF-kappaB signaling is engaged transiently when normal B lymphocytes respond to antigens, but lymphomas derived from these cells accumulate genetic lesions that constitutively activate NF-kappaB signaling.
openaire   +1 more source

[NF-kappaB inhibitor].

Nihon rinsho. Japanese journal of clinical medicine, 2012
Jun, Nakashima, Yutaka, Horiguchi, Yoshio, Ohno, Tatsuo, Gondo, Hisashi, Takeuchi, Masaaki, Tachibana   +5 more
openaire   +1 more source

NF-kappaB and apoptosis

Science, 1996
openaire   +1 more source

NF-kappaB

2011
openaire   +1 more source

ATRA, NF-kappaB and ATL.

Leukemia research, 2001
K, Tsukasaki, M, Tomonaga
openaire   +1 more source

NF-KAPPAB IN CRITICAL DISEASES

Shock, 2004
openaire   +1 more source