Results 101 to 110 of about 20,241 (230)

Applications of Artificial Intelligence (AI) for Diagnosis of Periodontal/Peri‐Implant Diseases: A Narrative Review

Journal of Oral Rehabilitation, EarlyView.
ABSTRACT Background Artificial intelligence (AI) and various subunits of AI such as artificial neural networks (ANN), Convolutional neural networks (CNNs), machine learning (ML), deep learning (DL) and deep neural networks (DNN) are being tried to diagnose and plan treatment for periodontal diseases.
Rupanjan Roy, Aditi Chopra, Shaswata Karmakar, Subraya Giliyar Bhat   +3 more
wiley   +1 more source

Genome-wide screening of mouse knockouts reveals novel genes required for normal integumentary and oculocutaneous structure and function. [PDF]

, 2019
Oculocutaneous syndromes are often due to mutations in single genes. In some cases, mouse models for these diseases exist in spontaneously occurring mutations, or in mice resulting from forward mutatagenesis screens.
Adissu, Hibret, Berberovic, Zorana, Clary, Dave, Eskandarian, Mohammad, Flenniken, Ann M, International Mouse Phenotyping Consortium, Lloyd, KC Kent, McKerlie, Colin, Moore, Bret A, Moshiri, Ala, Moshiri, Ata S, Murphy, Christopher J, Newbigging, Susan, Nutter, Lauryl MJ, Owen, Celeste, Thomasy, Sara M   +15 more
core  

Ebola virus VP35 induces high-level production of recombinant TPL-2–ABIN-2–NF-κB1 p105 complex in co-transfected HEK-293 cells [PDF]

, 2013
Activation of PKR (double-stranded-RNA-dependent protein kinase) by DNA plasmids decreases translation, and limits the amount of recombinant protein produced by transiently transfected HEK (human embryonic kidney)-293 cells.
Apostolaki, Baldi, Beinke, Beinke, Beinke, Beinke, Beinke, Belich, Bouwmeester, Ciechanover, Cohen, Coope, Costa, Dauber, Dumitru, Durocher, Elke MÜHLBERGER, Feng, Gantke, Geisse, George, Gray, Jia, Jia, Julia Janzen, Kabouridis, Kaufman, Lang, Liu, Nicholas A. Morrice, Papoutsopoulou, Pomerantz, Robinson, Roget, Sabrina Boussouf, Salmeron, Salmeron, Savinova, Schlaeger, Schumann, Steven Howell, Steven C. Ley, Thorsten Gantke, Waterfield, Waterfield, Wu, Yang, Zhao   +47 more
core   +1 more source

Positive social relations, loneliness, and immune system gene regulation

Annals of the New York Academy of Sciences, EarlyView.
In two studies of Korean adults, positive social relations—characterized by warmth, satisfaction, and trust—are inversely associated with conserved transcriptional response to adversity (CTRA) gene expression, independent of loneliness. Social flourishing may benefit human molecular well‐being, above and beyond the absence of social isolation or ...
Sung‐Ha Lee, Jeanyung Chey, Incheol Choi, Yoosik Youm, Steve Cole   +4 more
wiley   +1 more source

Innate immune responses induced by lipopolysaccharide and lipoteichoic acid in primary goat mammary epithelial cells

Journal of Animal Science and Biotechnology, 2017
Background Innate immune responses induced by in vitro stimulation of primary mammary epithelial cells (MEC) using Gram-negative lipopolysaccharide (LPS) and Gram-positive lipoteichoic acid (LTA) bacterial cell wall components are well- characterized in
Omar Bulgari, Xianwen Dong, Alfred L. Roca, Anna M. Caroli, Juan J. Loor   +4 more
doaj   +1 more source

Bank1 and NF-kappaB as key regulators in anti-nucleolar antibody development. [PDF]

PLoS ONE, 2018
Systemic autoimmune rheumatic disorders (SARD) represent important causes of morbidity and mortality in humans. The mechanisms triggering autoimmune responses are complex and involve a network of genetic factors.
Hammoudi Alkaissi, Said Havarinasab, Jesper Bo Nielsen, Peter Söderkvist, Per Hultman   +4 more
doaj   +1 more source

Utilization of HIV-1 envelope V3 to identify X4- and R5-specific Tat and LTR sequence signatures. [PDF]

, 2016
BACKGROUND: HIV-1 entry is a receptor-mediated process directed by the interaction of the viral envelope with the host cell CD4 molecule and one of two co-receptors, CCR5 or CXCR4.
Aiamkitsumrit, Benjamas, Antell, Gregory C, Dampier, Will, Hershberg, Uri, Jacobson, Jeffrey M, Kercher, Katherine, Krebs, Fred C, Nonnemacher, Michael R, Passic, Shendra, Pirrone, Vanessa, Schwartz, Gregory, Wigdahl, Brian, Williams, Jean W, Zhong, Wen   +13 more
core   +2 more sources

Obesity‐Induced Metabolic Priming Exacerbates SARS‐CoV‐2 Inflammation

Immunology, Volume 175, Issue 3, Page 323-338, July 2025.
Monocytes primed under obesogenic conditions, such as increased FFA levels (i.e., palmitate) exhibit exacerbated gene expression of inflammatory cytokines. The increased proinflammatory response of palmitate‐primed and SARS‐CoV‐2‐infected monocytes is not dependent on glycolytic metabolism but instead on the entry of FFAs into the mitochondria ...
Gustavo Gastão Davanzo, Bianca Gazieri Castelucci, Gabriela Fabiano de Souza, Stéfanie Primon Muraro, Larissa Menezes dos Reis, Isabella Bonilha de Oliveira, José Luís Fachi, João Victor Virgilio‐da‐Silva, Marcelo Rodrigues Berçot, Mariane Font Fernandes, Sarah de Oliveira, Nathalia Vitoria Pereira Araujo, Guilherme Ribeiro, Gisele de Castro, Webster Leonardo Guimarães Costa, Adriana Leandra Santoro, Gabriela Flavia Rodrigues‐Luiz, Helison Rafael P. do Carmo, Ikaro Breder, Marcelo A. Mori, Alessandro S. Farias, Daniel Martins‐de‐Souza, Joseph W. Guarnieri, Douglas C. Wallace, Marco Aurélio Ramirez Vinolo, José Luiz Proença‐Módena, Afshin Beheshti, Andrei C. Sposito, Pedro M. Moraes‐Vieira   +28 more
wiley   +1 more source

ASSOCIATION OF EXPRESSION OF NFKB1, HIF1, VEGFA, VEGFВ, BAX, BCL2 GENES WITH BIOCHEMICAL REMEDIATION IN PATIENTS WITH LOCALIZED PROSTATE CANCER

Исследования и практика в медицине, 2019
Aim. To identify the association of NFKB1, HIF1, VEGFA, VEGFB, BAX, BCL2 gene expression in prostate adenocarcinoma cells with biochemical recurrence of localized prostate cancer.Patients and methods.
Ph. S. Bova, O. I. Kit, A. Yu. Maksimov
doaj   +1 more source

ILC2 Diversity, Location, and Function in Pulmonary Disease

Immunological Reviews, Volume 332, Issue 1, July 2025.
ABSTRACT Type‐2 inflammation is driven by the production of canonical type‐2 cytokines IL‐4, IL‐5, and IL‐13. Type‐2 cytokines promote mucus production, innate immune cell recruitment, and smooth muscle contractility in mucosal tissues. These hallmarks of type‐2 inflammation are important contributors to the weep‐and‐sweep responses observed in the ...
Mukesh Verma, Uryan I. Can, R. Lee Reinhardt   +2 more
wiley   +1 more source