Results 101 to 110 of about 21,043 (239)

NFKB1 gene rs28362491 polymorphism is associated with the susceptibility of acute coronary syndrome [PDF]

Bioscience Reports, 2019
Abstract The acute coronary syndrome (ACS) is a complex disease where genetic and environmental factors are involved. NF-κB, a central regulator of inflammation, is involved in various inflammatory diseases. The aim of the present study was to explore the association between NFKB1 gene rs28362491 (-94ATTGins/del) polymorphism and ACS.
Si-Yu Jin, Jun-Yi Luo, Xiao-Mei Li, Fen Liu, Yi-Tong Ma, Xiao-Ming Gao, Yi-Ning Yang   +6 more
openaire   +3 more sources

Innate immune responses induced by lipopolysaccharide and lipoteichoic acid in primary goat mammary epithelial cells

Journal of Animal Science and Biotechnology, 2017
Background Innate immune responses induced by in vitro stimulation of primary mammary epithelial cells (MEC) using Gram-negative lipopolysaccharide (LPS) and Gram-positive lipoteichoic acid (LTA) bacterial cell wall components are well- characterized in
Omar Bulgari, Xianwen Dong, Alfred L. Roca, Anna M. Caroli, Juan J. Loor   +4 more
doaj   +1 more source

Identification of Novel Type 2 Diabetes Candidate Genes Involved in the Crosstalk between the Mitochondrial and the Insulin Signaling Systems [PDF]

, 2012
Type 2 Diabetes (T2D) is a highly prevalent chronic metabolic disease with strong co-morbidity with obesity and cardiovascular diseases. There is growing evidence supporting the notion that a crosstalk between mitochondria and the insulin signaling ...
, , Bonàs-Guarch, Sílvia, Draghici, Sorin, Dupuis, Josée, Florez, Jose C., Mercader, Josep M., Mora, Sílvia, Planet, Evarist, Puiggros, Montserrat, Ribas, Vicent, Rodriguez-Cuenca, Sergio, Sebastian, David, Segrè, Ayellet V., Sorianello, Eleonora, Torrents, David, Vidal-Puig, Antoni, Yang, Chenjing, Zorzano, Antonio   +18 more
core   +3 more sources

A patient‐derived orthotopic xenograft model unveils metastatic dynamics in head and neck squamous cell carcinoma

The FEBS Journal, EarlyView.
Metastasis in head and neck squamous cell carcinoma (HNSC) poses significant clinical challenges. This proof‐of‐concept study establishes patient‐derived orthotopic xenografts (PDOXs) as advanced models that closely replicate primary HNSC tumours, including local lymph node metastasis and the intricate cancer–stroma interaction.
Yuchen Bai, Benjamin Blyth, Jarryd Boath, Qiji Deng, Ruihong Huang, Charbel Darido   +5 more
wiley   +1 more source

Association of NFKB1 and NFKBIA gene polymorphisms with susceptibility of gastric cancer [PDF]

Tumor Biology, 2017
Xianyou county of Fujian province, located on the southeast coastal of China, has higher gastric cancer mortality. Chronic inflammation plays an important role in the occurrence of gastric cancer, in which the nuclear factor-κB signaling pathway of the inflammatory reaction begins and plays an important role in the amplification process.
Baoying Liu, Yuanhua Cai, Chuancheng Wu, Dan Li   +3 more
openaire   +3 more sources

The immune response mediator genes polymorphic variants as predictors of the etanercept efficacy in juvenile idiopathic arthritis

Russian Open Medical Journal, 2018
Objective ― The aim of the study was to investigate the relationship of the alleles and genotypes of the immune response mediator genes polymorphic loci (rs1800629, rs909253, rs16944, rs6822844, rs2104286, rs1800795, rs1800872, rs3087243, rs755622 ...
Liliia Sh. Nazarova, Ksenia V. Danilko, Viktor A. Malievsky, Akhat B. Bakirov, Tatiana V. Viktorova   +4 more
doaj   +1 more source

Genome-wide screening of mouse knockouts reveals novel genes required for normal integumentary and oculocutaneous structure and function. [PDF]

, 2019
Oculocutaneous syndromes are often due to mutations in single genes. In some cases, mouse models for these diseases exist in spontaneously occurring mutations, or in mice resulting from forward mutatagenesis screens.
Adissu, Hibret, Berberovic, Zorana, Clary, Dave, Eskandarian, Mohammad, Flenniken, Ann M, International Mouse Phenotyping Consortium, Lloyd, KC Kent, McKerlie, Colin, Moore, Bret A, Moshiri, Ala, Moshiri, Ata S, Murphy, Christopher J, Newbigging, Susan, Nutter, Lauryl MJ, Owen, Celeste, Thomasy, Sara M   +15 more
core  

Applications of Artificial Intelligence (AI) for Diagnosis of Periodontal/Peri‐Implant Diseases: A Narrative Review

Journal of Oral Rehabilitation, EarlyView.
ABSTRACT Background Artificial intelligence (AI) and various subunits of AI such as artificial neural networks (ANN), Convolutional neural networks (CNNs), machine learning (ML), deep learning (DL) and deep neural networks (DNN) are being tried to diagnose and plan treatment for periodontal diseases.
Rupanjan Roy, Aditi Chopra, Shaswata Karmakar, Subraya Giliyar Bhat   +3 more
wiley   +1 more source

Genome-wide association study of treatment refractory schizophrenia in Han Chinese. [PDF]

PLoS ONE, 2012
We report the first genome-wide association study of a joint analysis using 795 Han Chinese individuals with treatment-refractory schizophrenia (TRS) and 806 controls. Three loci showed suggestive significant association with TRS were identified.
Ying-Jay Liou, Hui-Hung Wang, Ming-Ta Michael Lee, Sheng-Chang Wang, Hung-Lun Chiang, Cheng-Chung Chen, Ching-Hua Lin, Ming-Shun Chung, Chien-Cheng Kuo, Ding-Lieh Liao, Ching-Kuan Wu, Chih-Min Liu, Yu-Li Liu, Hai-Gwo Hwu, I-Ching Lai, Shih-Jen Tsai, Chia-Hsiang Chen, Hui-Fen Liu, Yi-Chun Chou, Chien-Hsiun Chen, Yuan-Tsong Chen, Chen-Jee Hong, Jer-Yuarn Wu   +22 more
doaj   +1 more source

Exome analysis of rare and common variants within the NOD signaling pathway [PDF]

, 2017
Pediatric inflammatory bowel disease (pIBD) is a chronic heterogeneous disorder. This study looks at the burden of common and rare coding mutations within 41 genes comprising the NOD signaling pathway in pIBD patients.
Afzal, Nadeem A., Andreoletti, Gaia, Batra, Akshay, Beattie, R. Mark, Christenson, Kathy, Coelho, Tracy, Ennis, Sarah, Haggarty, Rachel, Mort, Matthew, Petersen, Britt-Sabina, Shakhnovich, Valentina   +10 more
core   +1 more source