АНАЛИЗ АССОЦИАЦИЙ ПОЛИМОРФНОГО ЛОКУСА rs28362491 ГЕНА NFKB1 С РИСКОМ РАЗВИТИЯ РАКА ЖЕЛУДКА [PDF]
С Мустафин+1 more
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What's new? Tumor necrosis factor (TNF) can promote tumor resistance to immune checkpoint inhibitors (ICIs), which are now the standard treatment for advanced melanoma patients. Here, in an advanced melanoma patient cohort, TNF was investigated for a possible predictive relationship with ICI response. Assessments show that after 12 weeks of ICI therapy,
Mathieu Virazels+18 more
wiley +1 more source
IS -94INS/DELATTG POLYMORPHISM IN THE NUCLEAR FACTOR KAPPA-B1 GENE (NFKB1) ASSOCIATED WITH NECROTIZING ENTEROCOLITIS? [PDF]
Danielle Lopes Teixeira Ferdinando+3 more
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Changes in multi‐gene cancer panels for children: A 4‐year retrospective review
Abstract The multi‐gene panel is the most utilized genetic test to evaluate for germline cancer predisposition syndromes. However, the rate of change of commercial multigene panels is not well understood, and its value as a standalone test has also not been investigated.
Elise G. Williams+4 more
wiley +1 more source
mRNA Expression of GATA3, FOXP3, TBX21, STAT3, NFKB1, and MAPK8 Transcription Factors in Humans and Their Cooperative Interactions Long-Term after Exposure to Chronic Radiation [PDF]
В. С. Никифоров+1 more
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Aging and Altered Gravity: A Cellular Perspective
We propose that, unlike biological aging, where Primary hallmarks initiate damage, spaceflight may trigger a feedback loop between Antagonistic and Integrative hallmarks, driving accelerated aging. Returning to 1 g restores proper signaling and breaks the cycle.
Sharon van Rijthoven+1 more
wiley +1 more source
Vasopressin‐Sensitive Aqp2 Regulation Mediated by the TAZ‐NR4A1 Axis in Renal Collecting Duct Cells
The TAZ‐NR4A1 axis was identified as a critical regulator of vasopressin‐induced AQP2 expression, essential for water homeostasis. Conditional TAZ‐knockout mice showed polyuria and a significant decrease in AQP2 expression in collecting ducts. In mpkCCDc11 cells, TAZ knockdown significantly impaired vasopressin‐mediated AQP2 expression independently of
Hong Seok Choi+6 more
wiley +1 more source
In this study, NFKB2 was verified to have a significant genetic effect on FAs. Knockdown of NFKB2 significantly reduced triglyceride concentrations, lipid droplet secretion, and the expressions of 17 key genes involved in lipid metabolism pathways, including PI3K‐AKT, NF‐κB, MAPK, adipocytokine, PPAR, and AMPK signaling pathways.
Lijun Shi+5 more
wiley +1 more source
Circulating Monocytes Act as a Common Trigger for the Calcification Paradox of Osteoporosis and Carotid Atherosclerosis via TGFB1-SP1 and TNFSF10-NFKB1 Axis [PDF]
Ziliang Zeng+16 more
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Altered mRNA Expression of NFKB1 and NFKB2 Genes in Penile Lichen Sclerosus, Penile Cancer and Zoon Balanitis [PDF]
Piotr Wierzbicki+7 more
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